Results 241 to 250 of about 2,367,532 (360)

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim   +37 more
wiley   +1 more source

Kidney transplantation in Alport syndrome: A genotype-guided case series and literature review. [PDF]

open access: yesTurk J Surg
Gavrilovska-Brzanov A   +8 more
europepmc   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong   +13 more
wiley   +1 more source

Supratherapeutic drug concentration triggers: A novel data‐driven approach to assess their value for medication safety surveillance in intensive care

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Electronic triggers (e‐triggers) are used as screening signals to detect potential adverse drug events (ADEs) and offer an effective system level approach for medication safety surveillance. Their clinical utility is typically evaluated through time‐consuming manual chart review by experts, limiting implementation.
Anne Paulien Langermans   +40 more
wiley   +1 more source

Changes in maintenance immunosuppression after pediatric kidney transplantation-a report from the Nordic pediatric kidney transplantation registry. [PDF]

open access: yesPediatr Nephrol
Kaijansinkko H   +11 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

WCN25-3335 PREDICTIVE FOCTORS FOR THE USE OF HEMODIALYSIS DURING SEVERE ACUTE KIDNEY INJURY FOLLOWING PRE-ECLAMPSIA

open access: yesKidney International Reports
Driss Benali   +4 more
doaj   +1 more source

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