Results 191 to 200 of about 32,146 (308)

Retrospective comparison of the clinical effects of oral semaglutide and SGLT2 inhibitors treatment in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This retrospective study compared oral semaglutide and SGLT2 inhibitors in patients with type 2 diabetes over 6 months. Both treatments significantly reduced HbA1c, body weight, and fat mass. Although the reduction in fat mass was comparable, changes in skeletal muscle mass tended to be less favorable with SGLT2 inhibitors than with oral semaglutide ...
Yasuhiro Omori, Ryota Usui, Yuji Yamazaki, Hitoshi Kuwata, Yoshiyuki Hamamoto, Yuichiro Yamada, Yutaka Seino   +6 more
wiley   +1 more source

Spatial and Temporal Expression Patterns of EDA2R, PCDH9, and TRAF7 in <i>Yotari</i> (<i>Dab1^-/-</i>) Mice: Implicationsfor Understanding CAKUT Pathogenesis. [PDF]

Int J Mol Sci
Komić J, Kelam N, Racetin A, Filipović N, Saraga-Babić M, Ihara D, Katsuyama Y, Vukojević K.   +7 more
europepmc   +1 more source

Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetic retinopathy (DR) is a prevalent chronic complication of type 2 diabetes mellitus (T2DM), contributing significantly to vision impairment. Circular RNAs (circRNAs) have emerged as key regulators in the pathogenesis of DR.
Wencheng An, Bingyan Wang, Fang Chen, Bo An, Shujing Zhou, Lin Jiang, Zhijun Cui, Xiaohong Ou, Wei Huang, Huixian Yan   +9 more
wiley   +1 more source

Comparable renal effects of histidine-tryptophan-ketoglutarate and DelNido cardioplegia in a porcine model of cardiac arrest. [PDF]

Ren Fail
Dieterlen MT, Kang J, Schütte P, Klaeske K, Oßmann S, Kiefer P, Vollroth M, Borger MA, Hoyer A.   +8 more
europepmc   +1 more source

Mechanisms of hesperetin in alleviating diabetic nephropathy: Network pharmacology, molecular docking, and experimental validation

Journal of Diabetes Investigation, EarlyView.
Hesperetin increases cell viability and reduces cell apoptosis, ferroptosis, release of inflammatory cytokines, and oxidative stress of human kidney tubular cells via repressing IGF1R expression. ABSTRACT Background Diabetic nephropathy (DN) accounts for approximately 50% of chronic kidney disease cases.
Yiwen Guo, Fengjiao Zhang, Yu Jin, Menglu Zhu, Zhiqiang Kang   +4 more
wiley   +1 more source

Induction of Nephron-Ductal Dual Lineages via Early Retinoic Acid Signaling Establishes a Platform for Fully Patterned Kidney Organoids. [PDF]

Adv Healthc Mater
Lim JH, Kim S, Lee DH, Kim DH, Lee HB, Son YS, Son MY, Oh SJ, Lee JY, Lee MO, Cho HS, Kim DS, Jung CR, Kang HM.   +13 more
europepmc   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source

Metastatic Bellini Duct Carcinoma: A Case Report and Literature Review. [PDF]

Cureus
El Maoudda H, Zouiten O, Mohtaram A, Afani L, El Fadli M, Belbaraka R.   +5 more
europepmc   +1 more source

Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment

Journal of Small Animal Practice, EarlyView.
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley   +1 more source

TFAP2A orchestrates gene regulatory networks and tubular architecture in kidney outer medullary collecting ducts. [PDF]

JCI Insight
Leiz J, López-Cayuqueo KI, Cao S, Gerhardt LM, Hinze C, Schmidt-Ott KM.   +5 more
europepmc   +1 more source