Results 281 to 290 of about 134,704 (353)

Aberrant activation of IL-6/JAK/STAT3/FOSL1 signaling induces renal abnormalities in a Xenopus model of Joubert syndrome-related disorders. [PDF]

J Biol Chem
Uuganbayar U, Ninomiya H, Shimada IS, Yamada C, Kanie M, Kawai S, Asai T, Miyoshi-Akiyama T, Itoh M, Hashimoto Y, Kato Y.   +10 more
europepmc   +1 more source

Silicon‐Based Agent Attenuates Age‐Related Spermatogenesis Disorder

International Journal of Urology, EarlyView.
ABSTRACT Objectives The progressive decline in birth rates due to delayed marriage has become a significant issue in developed countries, with male spermatogenetic capabilities gradually declining with age. This study evaluated the effectiveness of a silicon‐based agent (Si‐based) that efficiently generates hydrogen in the body to improve spermatogenic
Sohei Kuribayashi, Shinichiro Fukuhara, Hiroaki Kitakaze, Go Tsujimura, Takahiro Imanaka, Norichika Ueda, Kentaro Takezawa, Hikaru Kobayashi, Ryoichi Imamura, Norio Nonomura   +9 more
wiley   +1 more source

Application of SGLT-2 inhibitors in non-diabetic CKD: mechanisms, efficacy, and safety. [PDF]

Front Med (Lausanne)
Zhang B, Deng L.
europepmc   +1 more source

The loss of the urea cycle and ornithine metabolism in different insect orders: An omics approach

Insect Molecular Biology, EarlyView.
Among urea cycle enzymes, only the nitric oxide synthase gene is universally present across insect genomes. All Hemiptera species lack the enzymes needed to convert citrulline to arginine, and some also lack the pathway from arginine to ornithine. Putrescine and spermidine synthesis is conserved in all insects, but aphids lack the capability to produce
Jessica Cristina Silva Martins, Héctor Antônio Assunção Romão, Carolina Kurotusch Canettieri, Amanda Caetano Cercilian, Patrícia Rasteiro Ordiale Oliveira, Clelia Ferreira, Walter R. Terra, Renata de Oliveira Dias   +7 more
wiley   +1 more source

Naringin mitigated doxorubicin-induced kidney injury by the reduction of oxidative stress and inflammation with a synergistic anticancer effect. [PDF]

BMC Pharmacol Toxicol
Gad NS, Shabana SM, Amer ME, Othman AI, El-Missiry MA.   +4 more
europepmc   +1 more source

METTL3/YTHDF3 m6A axis promotes ferroptosis in diabetic kidney disease by stabilizing TfR1

Journal of Diabetes Investigation, EarlyView.
METTL3/YTHDF3 m6A axis promoted ferroptosis in DKD by stabilizing TfR1, which could provide a reference for DKD treatment. ABSTRACT Objective Diabetic kidney disease (DKD) is a common complication of diabetes. N6‐Methyladenosine (m6A) modification is a widely studied epigenetic mechanism.
Jinmei Zhang, Xiaoping Zhou, Bin Wang, Yan Yin, Daihao Wei, Kun Li   +5 more
wiley   +1 more source

Concomitant Wilms' tumor and renal cell carcinoma: Challenges in management and a case report. [PDF]

Int J Surg Case Rep
Mbwambo OJ, Yusuph M, Mwakipunda LE, Mbwambo J, Mremi A, Ngowi BN.   +5 more
europepmc   +1 more source

The Pathology and Blood Biochemistry of Juvenile Lates calcarifer on Diets Contaminated With Mycotoxins, Histamines and Rancid Fats—A Case Study

Journal of Fish Diseases, EarlyView.
ABSTRACT Mycotoxins, originating from contaminated raw materials or suboptimal feed storage, are a growing concern in tropical aquaculture. Common fungi such as Aspergillus spp. and Fusarium spp. produce mycotoxins including aflatoxin, fumonisin, deoxynivalenol and zearalenone. High doses or prolonged exposure (weeks) to low doses of these mycotoxins (<
Aidan Kwok, Jose A. Domingos, Joseph Oh, Piero Chan, Joyce J. L. Ong, Leo Nankervis, Jeffrey Ling, Robert Nichol, Susan Gibson‐Kueh   +8 more
wiley   +1 more source

The effects of methamphetamine intoxication on acute kidney injury in Iraqi male addicts. [PDF]

Toxicol Rep
Mirza SA, Mohammed NS, Ali ZQ, Mohamed AS.   +3 more
europepmc   +1 more source

Modulation of Sodium and Ammonia Transporters in the Context of Viral Gill Diseases in Common Carp (Cyprinus carpio)

Journal of Fish Diseases, EarlyView.
ABSTRACT Osmoregulation and ammonia removal are among key physiological processes that take place in gills and affect fish homeostasis and well‐being. These processes can be disrupted by numerous environmental factors, but also by viral infections, especially those leading to severe gill disorders.
Maria Zawisza, Muhammad Abdullah, Magdalena Marcinkowska, Marek Matras, Krzysztof Rakus, Mikolaj Adamek   +5 more
wiley   +1 more source