Results 191 to 200 of about 31,728 (253)

Predicting offer burden to optimize batch sizes in simultaneously expiring kidney offers. [PDF]

Front Artif Intell
Berry S, Görgülü B, Tunç S, Cevik M.
europepmc   +1 more source

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai, Shriarjun Shastry, Morgan R. Hurst, Arianna Minzoni, Eduardo Barbieri, Luke Remmler, Eugene N. Muratov, Michael A. Daniele, Stefano Menegatti, Alexander Tropsha   +9 more
wiley   +1 more source

Ureteral reconstruction is safe and successful in poorly functioning kidneys. [PDF]

Front Urol
Grimaud LW, Sury K, Salvino M, Livingston A, Lentz AC, Peterson AC.   +5 more
europepmc   +1 more source

Layered double hydroxides‐based nanozymes for effective biomedical applications: A review and future perspectives

BMEMat, EarlyView.
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui, Lu Zhang, Junyi Li, Yue Chen, Sheng Dai, Manfred F. Maitz, Ansha Zhao, Ping Yang   +7 more
wiley   +1 more source

ETP-specific-knockout mice reveal endotrophin as a key regulator of kidney fibrosis in ischemia-reperfusion injury models. [PDF]

Exp Mol Med
Kim DS, Funcke JB, Chen S, Min K, Onodera T, Kim M, Lin Q, Joung C, Velasco J, Virostek M, Walendzik K, Hiremath C, Marciano DK, Scherer PE.   +13 more
europepmc   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

The detrimental effects of microplastic exposure on kidney function. [PDF]

Front Med (Lausanne)
Jiang N, Zheng X, Zhang N, Cao Y.
europepmc   +1 more source

The roles of tertiary lymphoid structures in orchestrating immune responses in peripheral organs. [PDF]

Inflamm Regen
Taniguchi K, Yoshikawa T, Yanagita M.
europepmc   +1 more source

MRI annotation using an inversion-based preprocessing for CT model adaptation. [PDF]

Eur Radiol Exp
Häntze H, Xu L, Rattunde MN, Donle L, Dorfner FJ, Hering A, Nawabi J, Adams LC, Bressem KK.   +8 more
europepmc   +1 more source