Results 221 to 230 of about 1,582,096 (296)

Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

British Journal of Clinical Pharmacology, EarlyView.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus, Pauline Schiro, Jean‐Luc Faillie, Romane Freppel, Johana Béné, Claire de Canecaude, François Montastruc   +6 more
wiley   +1 more source

Correlation between real sieving coefficient determined using novel lab-scale module and pore structure of hemodiafiltration membranes. [PDF]

J Artif Organs
Ichikawa M, Fukuda M, Morikawa T, Takeuchi K, Sakai K.   +4 more
europepmc   +1 more source

Kidneys for Transplantation

, 1975

core  

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Fabry Disease: Integrating Molecular Pathophysiology, Precision Diagnosis, and Artificial Intelligence Toward Precision Medicine. [PDF]

Cells
Biddeci G, Spinelli G, Colomba P, Anania M, Duro G, Di Blasi F.   +5 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Bullying for Kidneys?

, 1991
Wight, Jeremy
core  

Spatial transcriptomic analysis of kidney biopsies identifies activation of complement and SPP1 networks in <i>Staphylococcus</i> infection-associated glomerulonephritis. [PDF]

Front Nephrol
Karaiskos S, Santana-Quintero L, Bott C, Paul R, Brodsky SV, Ayoub I, Parikh SV, Rovin BH, Nadasdy T, Nakhasi HL, Gannavaram S, Satoskar AA.   +11 more
europepmc   +1 more source

Kidneys for Transplant

, 1983

core  

A novel preoperative simulation approach for pediatric kidney transplantation to support donor-recipient size matching using dialysis fluid-enhanced CT imaging and 3D printing. [PDF]

Front Transplant
Bojstedt J, Gordon Murkes L, Tsirkos V, Nordström J.   +3 more
europepmc   +1 more source