Results 131 to 140 of about 237,290 (266)

Parallel processing of T cells and natural killer cells to enhance <i>in vivo</i>CAR T cell activity against blood and solid cancers. [PDF]

Clin Transl Immunology
Dobson LJ, Marron PW, Drabble AH, Liyanage TD, Pe KC, Slaney CY, Hock BD, McLellan AD.   +7 more
europepmc   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

Natural killer cells: roundup [PDF]

Immunological Reviews, 2006
openaire   +2 more sources

Correction: Natural killer (NK) cells with downregulated activating receptors and IL-10 production promote Trypanosoma cruzi T-cell responses in subjects in the Chronic phase of Trypanosoma cruzi infection: An exploratory immunological analysis. [PDF]

PLoS Negl Trop Dis
Elias MJ, Cesar G, Alvarez MG, Podhorzer A, Caputo MB, Albizu CL, Carrega M, Conte FAT, Natale MA, Albareda MC, Lococo B, Laucella SA.   +11 more
europepmc   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Invariant Natural Killer T Cell-Based Immunotherapy Using α-Galactosylceramide-Pulsed CD14⁺ Monocytes for Advanced Gallbladder Cancer. [PDF]

Eur J Case Rep Intern Med
Hanada K, Kobayashi K.
europepmc   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Natural killer cells in preeclampsia: an overview of current research. [PDF]

Front Immunol
Zhang Y, Su H, Zhang Y, Chen Q, Meng Y, Zhang C, Bi X, Li Q, Yang W.   +8 more
europepmc   +1 more source

Innate Immune Cells in Non-Small Cell Lung Cancer: Roles in Tumor Progression and Therapeutic Responses. [PDF]

Cancer Innov
Liu J, Jia J, Wang C, Zhou Z, Cheng Z, Zhang Z, Jiang X, Huang Z, Li C.   +8 more
europepmc   +1 more source