Results 181 to 190 of about 30,853 (255)

Identification and protective efficacy characterization of novel immunogenic antigens for Salmonella Enteritidis vaccines. [PDF]

Poult Sci
Zhao Y, Li G, Li YA, Li Q, Shi H.
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Proteome profiles of esophageal squamous cell carcinoma tie mitochondrial complex I to immunotherapy. [PDF]

EMBO Mol Med
Ma F, Li Y, Xiang C, Wang B, Lv J, Shang Z, Zhang W, Qin Z, Pu Y, Li K, Wei J, Tan SB, Feng J, Teng H, Zhang P, Deng J, Wang Y, Zhang C, Tian S, Li G, Kang M, Du C, Han Y, Ding C.   +23 more
europepmc   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Synthetic biology of oncolytic bacteria: Comparative microbial chassis and precise killing strategies. [PDF]

Toxicol Rep
Hadid MA, Shaikhli NHA, Suhail OK, Hameed ST, Challoob MA.   +4 more
europepmc   +1 more source

On Geometric Phase Model in the Theory of Curves With Myller Configuration

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this paper, we introduce a linearly polarized light wave in an optical fiber and rotation of the polarization plane through the Frenet‐type frame with Myller configuration. Since the geometric evaluation and interpretations of a polarized light wave are associated with geometric phase, a new type of geometric phase model has been ...
Zehra İşbilir, Bahar Doğan Yazıcı, Murat Tosun   +2 more
wiley   +1 more source

Plying potency assays for immunotherapy of solid tumors. [PDF]

Front Immunol
Burns JS, Gjeta R, Lesný P, Vives J.
europepmc   +1 more source

Conserving wildlife through demand reduction and supply alternatives: Two experiments in restaurants in Kinshasa

People and Nature, EarlyView.
Abstract High aggregate levels of wildlife consumption in cities in Central Africa highlight the need for solutions that balance wildlife protection, local livelihoods and the relational values between people and nature. This study explores the impacts of demand‐ and supply‐side interventions on wild meat consumption through two randomized control ...
Abdoulaye Cisse, Gabriel Englander, Daniel J. Ingram   +2 more
wiley   +1 more source

Oncostatin-M ligand-based CAR-T therapy displays robust anti-tumor activity against osteosarcoma. [PDF]

BMC Med
Feinberg D, Uppin V, Eid S, Fritz C, Hitomi M, Radhakrishnan A, Klatt K, Choi SH, Myers JT, Bhatt A, Stearns D, Pateva I, Burke ZDC, Huang AY, Schwartz GK, Parameswaran R.   +15 more
europepmc   +1 more source

Bt agave: why it is time to explore a new biotechnological frontier

Pest Management Science, EarlyView.
Drylands cover 41% of Earth, requiring sustainable crops. Agave, drought‐ and heat‐adapted, offers high‐value products with low water needs. Pests limit yield, yet Bacillus thuringiensis (Bt) Cry proteins, successful in other plants, remain unexploited in Agave.
Aline Vitória Corim Marim, Marcelo Falsarella Carazzolle, Gonçalo Amarante Guimarães Pereira, Carolina Rossi De Oliveira   +3 more
wiley   +1 more source