Results 221 to 230 of about 2,580,938 (299)

ERRATUM: Value of soluble fms-like tyrosine kinase 1 for predicting acute pancreatitis severity: a systematic review and meta-analysis. [PDF]

Rev Assoc Med Bras (1992)
europepmc   +1 more source

Therapeutic effects of Melittin acupoint injection on rheumatoid arthritis through autophagy activation and PI3K/AKT/mTOR pathway inhibition. [PDF]

Quant Imaging Med Surg
Xi W, Liu F, Zhong G, Chen F, Xie Y, Lai M, He Q, Lu Y, Zhang J, Chen Y, Meng L, Yang L.   +11 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Targeting cell cycle in leukemia: "Is palbociclib the game-changer?": A review. [PDF]

Medicine (Baltimore)
Azizan MA, Abeden Z, Shamsuddin NHN, Ahid F, Mohd Yusoff N, Ismail MN, Ng SK, Isa A.   +7 more
europepmc   +1 more source

Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

EMBO Journal, 1998
M. Saitoh, H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Yasuhiro Sawada, M. Kawabata, K. Miyazono, H. Ichijo   +8 more
semanticscholar   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Fusions4U: a resource of validated and annotated gene fusions in 328 cancer cell lines. [PDF]

BMC Cancer
Alamshahi A, Persson H.
europepmc   +1 more source

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

Nature, 1999
D. Fulton, J. Gratton, T. Mccabe, J. Fontana, Y. Fujio, K. Walsh, T. Franke, A. Papapetropoulos, W. Sessa   +8 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Advancing Hepatocellular Carcinoma Therapy with Next-Generation Molecular and Immunotherapeutics. [PDF]

J Hepatocell Carcinoma
Hassan M, Hussain I, Ahmad K, Zafar S, Khalid A, Haseeb M, Hussain N, Ghafar MA.   +7 more
europepmc   +1 more source