Results 331 to 340 of about 3,771,587 (392)
Some of the next articles are maybe not open access.
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
Current Opinion in Genetics & Development, 1994Signal transduction pathways that respond to external signals through the MAP kinase family of protein kinases are involved in diverse responses in eukaryotic cells. MAP kinases are one element in a series of kinases that serve to connect the plasma membrane with cytoplasmic and nuclear events. MAP kinases have the unusual feature that their activation
openaire +2 more sources
The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases)
Frontiers in Bioscience, 2008The human MAP kinase-interacting kinases (or MAP kinase signal-integrating kinases), Mnks, comprise a group of four proteins derived from two genes (Gene symbols: MKNK1 and MKNK2) by alternative splicing. Mnk1a/b differ at their C-termini, as do Mnk2a/2b: in each case, the a-form possesses a longer C-terminal region than the b-form, which lacks the MAP
Buxade, Maria +2 more
openaire +3 more sources
Phosphatidylinositol 3-kinase related kinases
Current Opinion in Immunology, 1996Studies in yeast, files and mammalian cells have uncovered a novel family of signal-transducing kinases which bear an evolutionary relationship to phosphatidylinositol 3-kinase. These phosphatidylinositol 3-kinase related enzymes play critical roles in DNA repair, V(D)J recombination and cell-cycle checkpoints, and their dysfunction leads to clinical ...
openaire +2 more sources
Kinase dysfunction and kinase inhibitors
Veterinary Dermatology, 2013With recent advances in molecular biology, abnormalities in cancer cells that contribute to dysregulation of cell survival and proliferation are being characterized with greater precision. Through this process, key abnormalities in cancer cells involving proteins that regulate signal transduction, migration, mitosis and other critical processes have ...
openaire +2 more sources
Cyclin dependent kinase activating kinases
Current Opinion in Cell Biology, 1996The cyclin dependent kinase activating kinase (CAK) has roles in both cell cycle regulation and transcription. CAK assembly is regulated either by additional protein binding or by phosphorylation. A recent comparison of this kinase from two yeast species shows that different proteins perform distinct roles and that the most studied CAK may function ...
openaire +2 more sources
The Protein Kinase Complement of the Human Genome
Science, 2002G. Manning +4 more
semanticscholar +1 more source
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
Nature, 1995D. Cross +4 more
semanticscholar +1 more source
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
Nature Reviews. Cancer, 2002I. Vivanco, C. Sawyers
semanticscholar +1 more source
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
Science, 1988S. Hanks, A. Quinn, T. Hunter
semanticscholar +1 more source