Results 291 to 300 of about 276,702 (351)

Electrochemical Biosensors for Cancer Biomarker Detection: Basic Concept, Design Strategy and Cutting‐Edge Development

open access: yesElectrochemical Science Advances, EarlyView.
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley   +1 more source

Rational engineering of allosteric protein switches byin silicoprediction of domain insertion sites

open access: yes
Wolf B   +10 more
europepmc   +1 more source

Ethylene signals through an ethylene receptor to modulate biofilm formation and root colonization in a beneficial plant-associated bacterium. [PDF]

open access: yesPLoS Genet
Carlew TS   +11 more
europepmc   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

open access: yesExploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang   +6 more
wiley   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

open access: yesExploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

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