Results 221 to 230 of about 1,477,881 (298)

DARKIN: a zero-shot benchmark for phosphosite-dark kinase association using protein language models. [PDF]

Bioinformatics
Sunar EA, Işık Z, Pekey M, Cinbiş RG, Tastan O.   +4 more
europepmc   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Stress-Activated Protein Kinase Pathways as Potential Targets for the Development of New Antifungals. [PDF]

J Fungi (Basel)
Alonso-Monge R, Guirao-Abad JP, Argüelles JC.   +2 more
europepmc   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

KSMoFinder-knowledge graph embedding of proteins and motifs for predicting kinases of human phosphosites. [PDF]

Bioinform Adv
Anandakrishnan M, Ross KE, Chen C, Vijay-Shanker K, Wu CH.   +4 more
europepmc   +1 more source

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

Advanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong   +8 more
wiley   +1 more source

Molecular identifiers of the evolutionarily conserved titin pseudokinase. [PDF]

Biochem J
Dorendorf T, Gravenhorst P, Mayans O.
europepmc   +1 more source

OmicIntegrator: A Simple and Versatile Tool for Meta-Analysis. [PDF]

Plants (Basel)
Gitman IFB, Grossi CEM, Arico DS, Mazzella MA, Ulloa RM.   +4 more
europepmc   +1 more source