Results 41 to 50 of about 19,754 (224)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
In Vivo Measurement of Mesokinesis in Gekko gecko: The Role of Cranial Kinesis during Gape Display, Feeding and Biting. [PDF]
PLoS ONE, 2015 Cranial kinesis refers to movements of skeletal sub-units relative to one another at mobile sutures within the skull. The presence and functional significance of cranial kinesis has been investigated in various vertebrates, with much of our understanding
Stéphane J Montuelle, Susan H Williams
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Wearable Technologies, 2022 The five times sit-to-stand test (FTSS) is an established functional test, used clinically as a measure of lower-limb strength, endurance and falls risk.
Barry R. Greene +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Jurnal Pembangunan dan Alam Lestari, 2012 Abstrak Tujuan penelitian ini adalah mengembangkan model simulasi kinesis untuk melihat daerah konsentrasi ikan kembung lelaki (Rastrelliger kanagurta) di wilayah Perairan Barat Sulawesi Selatan.
Sabrun - Jamil +3 more
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Kínesis, 2013 É com muita satisfação que apresentamos mais uma edição da Revista Kínesis. A presente edição é coroada com trabalhos de diversas instituições e centros de pesquisa em Filosofia do Brasil e alguns trabalhos do exterior.
João Antonio de Morais +4 more
doaj +1 more source
SPARCS: Stream-processing architecture applied in real-time cyber-physical security [PDF]
, 2019 In this paper, we showcase a complete, end-To-end, fault tolerant, bandwidth and latency optimized architecture for real time utilization of data from multiple sources that allows the collection, transport, storage, processing, and display of both raw ...
Boverhof, J +3 more
core +1 more source