Results 41 to 50 of about 17,503 (194)
Wearable Technologies, 2022 The five times sit-to-stand test (FTSS) is an established functional test, used clinically as a measure of lower-limb strength, endurance and falls risk.
Barry R. Greene +3 more
doaj +1 more source
Electronic Dance Music in Narrative Film [PDF]
, 2019 As a growing number of filmmakers are moving away from the traditional model of orchestral underscoring in favor of a more contemporary approach to film sound, electronic dance music (EDM) is playing an increasingly important role in current soundtrack ...
Filoseta, Roberto
core +2 more sources
ISOMETRY OF EGG SIZE IN A TEXAS POPULATION OF THE TURTLE STERNOTHERUS ODORATUS THAT EXHIBITS A NEARLY FIXED CLUTCH SIZE [PDF]
, 2020 In evaluating optimal egg-size theory and the effects of anatomical constraints on egg size in turtles, pivotal questions concern the significance of the relationship of egg size to female body size and whether the relationship is isometric or ...
Lindeman, Peter V.
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Jurnal Pembangunan dan Alam Lestari, 2012 Abstrak Tujuan penelitian ini adalah mengembangkan model simulasi kinesis untuk melihat daerah konsentrasi ikan kembung lelaki (Rastrelliger kanagurta) di wilayah Perairan Barat Sulawesi Selatan.
Sabrun - Jamil +3 more
doaj
Potential benefits, limitations and target product-profiles of odor-baited mosquito traps for malaria control in Africa. [PDF]
, 2010 BACKGROUND\ud \ud Traps baited with synthetic human odors have been proposed as suitable technologies for controlling malaria and other mosquito-borne diseases.
Okumu, Fredros O +4 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The kinesin Eg5 inhibitor K858 induces apoptosis but also survivin-related chemoresistance in breast cancer cells [PDF]
, 2016 Inhibitors of kinesin spindle protein Eg5 are characterized by pronounced antitumor activity. Our group has recently synthesized and screened a library of 1,3,4-thiadiazoline analogues with the pharmacophoric structure of K858, an Eg5 inhibitor.
CARRADORI, Simone +8 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source