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Prediction of In Vivo Kinetic Constants for Metabolism of Inhaled Vapors from Kinetic Constants Measured In Vitro

Toxicological Sciences, 1981
Benzene and toluene are metabolized by microsomal preparations in a closed metabolism flask. The Km values for benzene and toluene were 8.0 and 10.3 microM; the Vmax values were 17.2 and 20.8 nmol/g liver/min, respectively. By the use of a toxicokinetic model which acknowledges the potential for perfusion limitations on in vivo metabolism, the in vivo ...
R L, Hilderbrand   +2 more
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The Role of Effective Rate Constants in Interfacial Kinetics

MRS Proceedings, 1998
ABSTRACTA brief excerpt of a more comprehensive quantitative theoretical analysis on the role of effective rate constants in interfacial processes is given (in particular [1], see also [2,3]). Chemical incorporation, tracer incorporation and steady state electrical experiments are considered.
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Kinetic constants for methyl methacrylate polymerization

Journal of Colloid Science, 1955
Abstract Values for A ′ and C tr , m for methyl methacrylate polymerization betwen 20°C. and 98°C. are presented. These are important for accurate calculation of rates of initiation.
T.E Ferington, A.V Tobolsky
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Calculation of the kinetic rate constants

1999
Protein folding reactions can proceed according to a variety of different mechanisms. This chapter presents analytical solutions for kinetic rate constants and amplitudes for common reaction mechanisms.
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A priori rate constants for kinetic modeling

Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta), 2002
The advent of computer-aided methods for constructing detailed kinetic models of multicomponent reacting systems provides fresh motivation for the development of efficient and accurate methods for estimating rate constants. There is now the real likelihood that a priori rate estimates, formerly of primarily academic interest, could directly impact ...
R. Sumathi, William H. Green Jr.
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Kinetic constants for urate transport

American Journal of Physiology-Renal Physiology, 1982
I M, Weiner, J P, Tinker
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Chemical Kinetics in Constant-Pressure Systems

Journal of Chemical Education, 1999
A theory is developed for treating chemical kinetics in nonflow, constant-pressure systems. The procedure is straightforward and applicable to systems in which several reactions occur, subject to any given rate laws. A significant difference from kinetics at constant volume is that the varying volume precludes the use of concentrations to express the ...
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Formulation of the Velocity Constant in Chemical Kinetics

Nature, 1953
MUCH information on chemical kinetics has been accumulated in recent years. In many cases it is of high precision and of proved exactness, so that comparisons may be made with a fair degree of satisfaction of data presented for similar systems. Further, the exactness of some of the data makes it possible to use information obtained by different authors
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Computational Prediction of Kinetic Rate Constants

2006
Abstract : Report developed under SBIR/STTR contract for Topic #AF05-T010. The purpose of these efforts was to develop seamless, easy to use, efficient code to calculate electronic wave functions and potential energy surfaces of molecules and predict kinetic rate constants for reactions a priori.
Denis M. Reidy, Dmitry A. Altshuler
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