Results 51 to 60 of about 467,855 (300)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Elastic Constants of Quantum Solids by Path Integral Simulations

, 2000
Two methods are proposed to evaluate the second-order elastic constants of quantum mechanically treated solids. One method is based on path-integral simulations in the (NVT) ensemble using an estimator for elastic constants.
B. J. Berne, C. A. Swenson, C. Chakravarty, D. C. Wallace, D. Marx, D. R. Squire, D. S. Greywall, E. R. Dobbs, E. W. Draeger, H. R. Glyde, J. A. Barker, J. Wang, K. E. Schmidt, M. E. Tuckerman, M. E. Tuckerman, M. F. Herman, M. H. Müser, M. L. Klein, M. L. Klein, M. Parrinello, M. Parrinello, M. Sprik, Martin H. Müser, N. W. Ashcroft, Philipp Schöffel, R. A. Aziz, R. P. Feynman, S. Moroni   +27 more
core   +1 more source

KINETICS OF RECOMBINATION PROCESSES [PDF]

, 2002
In order to solve nonlinear kinetic equations for recombination reactions when the production of participating species is driven externally at a time-dependent rate, the authors establish a framework based on the correspondence between these equations ...
RAUH, H, STONEHAM, AM
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Classical and quantum three-dimensional integrable systems with axial symmetry

, 2007
We study the most general form of a three dimensional classical integrable system with axial symmetry and invariant under the axis reflection. We assume that the three constants of motion are the Hamiltonian, $H$, with the standard form of a kinetic part
Arscott F M, Eisenhart L P, Erdlyi A, Erdlyi A, Flammer C, G P Pronko, Gadella M, J Negro, M Gadella, Makarov A A, Meixner J, Meixner J, Miller W, Reed M, Stratton J A   +14 more
core   +2 more sources

$B$ Decay Constants from NRQCD with Dynamical Fermions [PDF]

, 1996
We present a lattice investigation of the heavy-light meson decay constants using Wilson light quarks and NRQCD heavy quarks, partially including the effects of dynamical sea quarks.
A. Ali Khan, A. Ali Khan, A. Duncan, B. A. Thacker, C. Allton, C. Bernard, C. T. H. Davies, C. T. H. Davies, C. T. H. Davies, E. Eichten, E. Eichten, J. H. Sloan, J. M. Flynn, J. Shigemitsu, K. M. Bitar, M. Crisafulli, M. Neubert, M. Neubert, P. Ball, P. Lepage, R. Baxter, S. Collins, S. Collins, S. Hashimoto, T. Onogi, U. M. Heller   +25 more
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The reactivity of α,β-unsaturated carboxylic acids. Part XVI. The kinetics of the reaction of cycloalkenecarboxylic and cycloalkenylacetic acids with diazodiphenylmethane in various alcohols [PDF]

Journal of the Serbian Chemical Society, 2002
The rate constants for the reaction of diazodiphenylmethane with 1-cyclopentenecarboxylic, 1-cycloheptenecarboxylic, cyclopent-1-enylacetic and cyclohept-1-enylacetic acids were determined in eight alcohols at 30 ºC using the appropriate UV-spectroscopic
Ušćumlić Gordana S., Nikolić Jasmina B., Krstić Vera V.   +2 more
doaj   +1 more source

Exploring solution ICAR ATRP of methyl acrylate with AIBN as azo initiator: a kinetic modeling and simulation study

Results in Materials, 2022
Supplementary techniques to atom transfer radical polymerization (ATRP) have been studied to reduce the concentration of catalytic complexes used, aiming at a less costly and more environmentally friendly process for synthesizing polymeric materials ...
Guilherme C.L. Faria, Emerson P. Lyra
doaj   +1 more source