Results 331 to 340 of about 115,854 (373)

The Spc105/Kre28 complex promotes mitotic error correction by outer kinetochore recruitment of Ipl1/Sli15. [PDF]

EMBO J
Dudziak A, Pleuger R, Schmidt J, Hamm F, Tendulkar S, Jänen K, Vetter IR, Singh S, Fischböck J, Herzog F, Westermann S.   +10 more
europepmc   +1 more source

dTAPL, A Method That Expedites the Discovery of Proteins Associated With Specific Genomic Loci in Plants

Plant Biotechnology Journal, EarlyView.
Fan Zhang, Tengfei Zhu, Conggui Peng, Zhen Zhuang, Yaping Tang, Zhi Yang, Shengbao Yang, Liyu Huang, Xu Wang   +8 more
wiley   +1 more source

Cytotoxicity of Atropisomeric [1,1′‐Binaphthalene]‐2,2′‐Diamines (BINAM) and Analogs in Human Cancer Cells: Enantioselectivity, Structure–Activity Relationships, and Mechanism

ChemMedChem, Volume 20, Issue 19, October 6, 2025.
It is reported for the first time that atropisomeric (R)‐[1,1′‐binaphthalene]‐2,2′‐diamine (R‐BINAM, 1(R)), but not (S)‐[1,1′‐binaphthalene]‐2,2′‐diamine (S‐BINAM, 1(S)), is a moderately potent spindle poison, causing antiproliferation, depolymerization of microtubules, multipolar spindles, pericentriolar material (PCM) fragmentation, mitotic ...
Malte Eichelbaum, Patrick J. Bednarski
wiley   +1 more source

The BUB1 and BUBR1 paralogs scaffold the kinetochore corona

Cmentowski V, Musacchio A.
europepmc   +1 more source

MoMad2 With a Conserved Function in the Spindle Assembly Checkpoint Is Required for Maintaining Appressorial Turgor Pressure and Pathogenicity of Rice Blast Fungus. [PDF]

Mol Plant Pathol
Shen T, Chen Q, Leontiou I, Wang R, Su M, Luo Q, Lu G, Wang Z, Li Y, Hardwick KG, Wang M.   +10 more
europepmc   +1 more source

Hierarchical Prediction and Perturbation of Chromatin Organization Reveal How Loop Domains Mediate Higher‐Order Architectures

Advanced Science, Volume 12, Issue 37, October 6, 2025.
HiCGen introduces a hierarchical deep learning framework to predict genome organization across spatial scales using DNA sequences and genomic features. The model enables cross‐cell‐type predictions and in silico perturbation analysis, revealing correlations between loop domains and higher‐order structures.
Jiachen Wei, Yue Xue, Yi Qin Gao
wiley   +1 more source

Architecture and Function of Holocentric CENP-A-Independent Kinetochores

Yu C, Sankaranarayanan SR, Cornilleau G, Howes A, Azumaya C, Zilberleyb I, Brillantes B, Cheung TK, Dec L, Loew D, Tran P, Rose CM, Drinnenberg IA, Ciferri C, Yatskevich S.   +14 more
europepmc   +1 more source

ZSCAN4 functions as a safeguard to maintain centromere integrity during oocyte meiosis. [PDF]

Genome Biol
Choi DY, Leem J, Lee C, Oh JS.
europepmc   +1 more source

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
wiley   +1 more source

Cell enlargement causes mitotic errors and aneuploidy in cells that evade senescence after CDK4/6 inhibition

Pareri AU, Losito M, Foijer F, Saurin AT.   +3 more
europepmc   +1 more source