Results 61 to 70 of about 7,883 (247)
The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference! [PDF]
, 2015 Kinetoplastids are unicellular, eukaryotic, flagellated protozoans containing the eponymous kinetoplast. Within this order, the family of trypanosomatids are responsible for some of the most serious human diseases, including Chagas disease (Trypanosoma ...
De Koning, Harry P. +2 more
core +1 more source
Sexual processes in the kinetoplastida
Parasitology, 1983 SUMMARYThe commonly held view that the kinetoplastida, and in particular trypanosomes, are asexual is largely derived from the principle that an organism is asexual until proved sexual. If the basis for this view is examined in detail, it largely arises from the lack of morphologically distinguishable gametes, the difficulties encountered in ...
openaire +2 more sources
Potential geographic displacement of Chagas disease vectors under climate change
Medical and Veterinary Entomology, Volume 39, Issue 4, Page 709-717, December 2025.As a result of modelling the potential distribution of 55 triatomine species in the Neotropical region, with climate change projected for up to 2050, we found no significant changes. With climate change projected for up to 2080 in the Neotropical region, we see a significant potential for the migration of 55 species of triatomines towards the Amazon ...
Leandro Schlemmer Brasil +7 more
wiley +1 more source
PLoS ONE, 2011 It has been known for decades that some insect-infecting trypanosomatids can survive in culture without heme supplementation while others cannot, and that this capability is associated with the presence of a betaproteobacterial endosymbiont in the ...
João M P Alves +8 more
doaj +1 more source
Metabolism and Functions of Trypanothione in the Kinetoplastida
Annual Review of Microbiology, 1992 Trypanosomatids differ from all other organisms in their ability to conjugate the sulfur-containing tripeptide, glutathione, and the polyamine, spermidine, to form trypanothione [N1,N8-bis(glutathionyl)spermidine]. Together with the NADPH-dependent flavoprotein, trypanothione reductase, the dithiol form of trypanothione provides an intracellular ...
Fairlamb, Alan H., Cerami, Anthony
openaire +3 more sources
Natural Products from Mexican Medicinal Plants as Promising Trypanocidal Drugs
ChemistrySelect, Volume 10, Issue 37, October 6, 2025.Chagas disease (American Trypanosomiasis) is caused by the protozoan Trypanosoma cruzi. Worldwide it is one of the seventeen neglected tropical diseases. There is a need of new drugs. This review assesses the literature (2012‐2024) of secondary metabolites isolated from Mexican plants active against this parasite.
Karla Daniela Rodríguez‐Hernández +2 more
wiley +1 more source
Aryl Phosphoramidates of 5-Phospho Erythronohydroxamic Acid, A New Class of Potent Trypanocidal Compounds [PDF]
, 2010 RNAi and enzymatic studies have shown the importance of 6-phosphogluconate dehydrogenase (6-PGDH) in Trypanosoma brucei for the parasite survival and make it an attractive drug target for the development of new treatments against human African ...
Alibu, Vincent P. +6 more
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The State of Beekeeping in India: Insights, Gaps, and Emerging Opportunities
Entomological Research, Volume 55, Issue 10, October 2025.ABSTRACT India's beekeeping industry primarily revolves around two domesticated honey bee species, Apis cerana and A. mellifera, which are central to commercial beekeeping. In addition, there are four wild honey bee species—A. dorsata, A. laboriosa (sympatric with A. dorsata), A. florea, and A. andreniformis (sympatric with A.
Sampat Ghosh +2 more
wiley +1 more source
Infection of a mammal by monogenetic insect trypanosomatids (Kinetoplastida, trypanosomatidae)
Memorias do Instituto Oswaldo Cruz, 1988 Monogenetic insect trypanosomatids of the genera Crithidia, Leptomonas and Herpetomonas, multiplied as in axenic cultures, for many months, in the lumen of the scent glands of the opossum Didelphis marsupialis.
Ana M. Jansen +2 more
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Pathogens, 2021 The genus Trypanosoma includes flagellated protozoa belonging to the family Trypanosomatidae (Euglenozoa, Kinetoplastida) that can infect humans and several animal species. The most studied species are those causing severe human pathology, such as Chagas
Alice Magri +2 more
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