Results 71 to 80 of about 7,883 (247)

Through the dark continent: African trypanosome development in the tsetse fly [PDF]

open access: yes, 2013
African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
core   +4 more sources

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone

open access: yesDrug Development Research, Volume 86, Issue 5, August 2025.
ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp   +4 more
wiley   +1 more source

Protein import into bacterial endosymbionts and evolving organelles

open access: yesThe FEBS Journal, Volume 292, Issue 12, Page 2992-3013, June 2025.
The acquisition of bacterial endosymbionts by ancient host cells followed by massive adaptation of the partners gave rise to mitochondria and plastids. Today, various systems with younger and less integrated endosymbionts provide insights into the initial steps in the endosymbiont to organelle transition.
Megan E. S. Sørensen   +3 more
wiley   +1 more source

The nucleolar DExD/H protein Hel66 is involved in ribosome biogenesis in Trypanosoma brucei

open access: yesScientific Reports, 2021
The biosynthesis of ribosomes is a complex cellular process involving ribosomal RNA, ribosomal proteins and several further trans-acting factors. DExD/H box proteins constitute the largest family of trans-acting protein factors involved in this process ...
Majeed Bakari-Soale   +6 more
doaj   +1 more source

Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality [PDF]

open access: yes, 2010
A Plasmodium falciparum hexose transporter (PfHT) has previously been shown to be a facilitative glucose and fructose transporter. Its expression in Xenopus laevis oocytes and the use of a glucose analogue inhibitor permitted chemical validation of PfHT ...
Doerig, C   +6 more
core   +2 more sources

A New Paramoeba Isolate From Florida Exhibits a Microtubule‐Bound Endosymbiont Closely Associated With the Host Nucleus

open access: yesJournal of Eukaryotic Microbiology, Volume 72, Issue 3, May/June 2025.
ABSTRACT The genera Paramoeba and Neoparamoeba, within the family Paramoebidae (order Dactylopodida), are distinguished by their dactylopodial pseudopodia and the presence of an intracellular eukaryotic symbiont, the Perkinsela‐like organism (PLO). Taxonomic classification within these genera has been challenging due to overlapping morphological traits
Yonas I. Tekle   +4 more
wiley   +1 more source

The genetics and genomics of Trypanosoma cruzi [PDF]

open access: yes, 2007
Trypanosoma cruzi is a kinetoplastid parasite that causes Chagas disease. Trypanosomes are unusual organisms in many aspects of its genetics and molecular and cellular biology and considered a paradigm of the exception of the rule in the eukaryotic ...
Vazquez, Martin Pablo
core  

A Narnavirus in the trypanosomatid protist plant pathogen Phytomonas serpens [PDF]

open access: yes, 2016
We describe here a new RNA virus (PserNV1) from the plant protist parasite Phytomonas serpens (family Trypanosomatidae, Kinetoplastida, supergroup Excavata).
Akopyants, Natalia S   +4 more
core   +2 more sources

Advanced DNA–Gold Biointerface for PCR‐Free Molecular Detection of Leishmania infantum

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 5, March 3, 2025.
The development of DNA–gold biointerface is proposed for the Polymerase Chain Reaction (PCR)‐free molecular detection of protozoan Leishmania infantum and the experimental and theoretical investigation of its surface properties, in terms of oligonucleotide probes grafting density and sensing interface isoelectric properties, toward the improvement of ...
Paolo Calorenni   +9 more
wiley   +1 more source

Trypanosoma cruzi infection enhances olfactory response in Triatoma pallidipennis Stål (Hemiptera: Triatominae) to compounds potentially useful for insect control

open access: yesMedical and Veterinary Entomology, Volume 39, Issue 1, Page 160-170, March 2025.
Triatoma pallidipennis is one of the main vectors of Trypanosoma cruzi, the causative agent of Chagas disease. Attractant activity of octenol, nonanal and a mixture of lactic acid, hexanoic acid and ammonium hydroxide on T. cruzi–infected and non‐infected T. pallidipennis nymphal stages.
Berenice Jiménez‐Santiago   +4 more
wiley   +1 more source

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