Functional Oxygen Sensitivity of Astrocytes [PDF]
, 2015 In terrestrial mammals, the oxygen storage capacity of the CNS is limited, and neuronal function is rapidly impaired if oxygen supply is interrupted even for a short period of time.
Abramov, AY +13 more
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Ammonia toxicity to the brain [PDF]
, 2018 Hyperammonemia can be caused by various acquired or inherited disorders such as urea cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in childhood than in adulthood.
Braissant, Olivier +2 more
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The Role Of Astrocytes In The Development Of Central Chemosensitivity [PDF]
, 2018 In the two decades since MECP2 was identified as the causative gene in the majority of Rett Syndrome (RTT) cases, transgenic mouse models have played a critical role in our understanding of this X-linked neurodevelopmental disease.
Patterson, Kelsey
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Evaluation of cultured cochlear fibrocytes as a cell replacement therapy: comparison with native fibrocytes [PDF]
, 2020 Fibrocyte degeneration in the cochlear lateral wall is one possible pathology of age-related metabolic hearing loss (presbyacusis). Fibrocytes play a role in potassium recycling and maintenance of the endocochlear potential (EP).
Osborn, Anya Helen
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Non-trivial dynamics in a model of glial membrane voltage driven by open potassium pores
, 2022 Despite the molecular evidence that close to linear steady state I-V relationship in mammalian astrocytes reflects a total current resulting from more than one differently regulated K+ conductances, detailed ODE models of membrane voltage Vm ...
Janjic, Predrag +2 more
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Molecular bases of K+ secretory cells in the inner ear: shared and distinct features between birds and mammals [PDF]
, 2016 In the cochlea, mammals maintain a uniquely high endolymphatic potential (EP), which is not observed in other vertebrate groups. However, a high [K+] is always present in the inner ear endolymph.
Hartmann, Anna-Maria +4 more
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The role of the inwardly rectifying potassium channel Kir5.1 in the distal convoluted tubule [PDF]
, 2018 In the kidney, inwardly rectifying K+ channels of the Kir (KCNJ) family are essential for the control of salt transport. In the basolateral membrane of distal convoluted tubules (DCT), Kir4.1 (KCNJ10) together with Kir5.1 (KCNJ16) appears to be relevant ...
Quintanova, Catarina Isabel Rina
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Special collection on inward rectifying K+ channels. [PDF]
Am J Physiol Cell Physiol, 2023 Denton JS, Delpire E.
europepmc +1 more source
Molecular profiling of CO2/pH-sensitive neurons in the locus coeruleus of bullfrogs reveals overlapping noradrenergic and glutamatergic cell identity. [PDF]
Comp Biochem Physiol A Mol Integr Physiol, 2023 Amaral-Silva L, Santin JM.
europepmc +1 more source
Editorial: 30th anniversary of the molecular cloning and identification of the Na-Cl cotransporter, NCC. [PDF]
Front Physiol, 2023 de Los Heros P, Ellison DH, Gamba G.
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