Results 81 to 90 of about 1,066 (149)

Inwardly rectifying potassium channels (KIR) in GtoPdb v.2025.3 [PDF]

The 2TM domain family of K channels are also known as the inward-rectifier K channel family. This family includes the strong inward-rectifier K channels (Kir2.x) that are constitutively active, the G-protein-activated inward-rectifier K channels (Kir3.x)
Adelman, John P., Clapham, David E., Hibino, Hiroshi, Inanobe, Atsushi, Jan, Lily Y., Karschin, Andreas, Kubo, Yoshihiro, Kurachi, Yoshihisa, Lazdunski, Michel, Miki, Takashi, Nichols, Colin G., Palmer, Lawrence G., Pearson, Wade L., Sackin, Henry, Seino, Susumu, Slesinger, Paul A., Tucker, Stephen, Vandenberg, Carol A.   +17 more
core   +2 more sources

Repeated seizure-induced brainstem neuroinflammation contributes to post-ictal ventilatory control dysfunction

Frontiers in Physiology
Patients with epilepsy face heightened risk of post-ictal cardiorespiratory suppression and sudden unexpected death in epilepsy (SUDEP). Studies have shown that neuroinflammation, mediated by the activation of microglia and astrocytes, may be a cause or ...
Wasif A. Osmani, Alexander Gallo, Madeline Tabor, Melissa Eilbes, Denise R. Cook-Snyder, Matthew R. Hodges, Matthew R. Hodges   +6 more
doaj   +1 more source

Kir4.1 channels contribute to astrocyte CO2/H+-sensitivity and the drive to breathe

Communications Biology
Astrocytes in the retrotrapezoid nucleus (RTN) stimulate breathing in response to CO2/H+, however, it is not clear how these cells detect changes in CO2/H+.
Colin M. Cleary, Jack L. Browning, Moritz Armbruster, Cleyton R. Sobrinho, Monica L. Strain, Sarvin Jahanbani, Jaseph Soto-Perez, Virginia E. Hawkins, Chris G. Dulla, Michelle L. Olsen, Daniel K. Mulkey   +10 more
doaj   +1 more source

Brain Aquaporin 4 in Hyperammonemia [PDF]

, 2010
In liver failure, congenital enzymopathies of the urea cycle, and other disorders, ammonia may not be properly detoxified and thus hyperammonemia ensues.
Cauli, Omar
core  

Inwardly rectifying potassium channels (KIR) in GtoPdb v.2025.4 [PDF]

The 2TM domain family of K channels are also known as the inward-rectifier K channel family. This family includes the strong inward-rectifier K channels (Kir2.x) that are constitutively active, the G protein-activated inward-rectifier K channels (Kir3.x)
Adelman, John P., Clapham, David E., Hibino, Hiroshi, Inanobe, Atsushi, Jan, Lily Y., Karschin, Andreas, Kubo, Yoshihiro, Kurachi, Yoshihisa, Lazdunski, Michel, Miki, Takashi, Nichols, Colin G., Palmer, Lawrence G., Pearson, Wade L., Sackin, Henry, Seino, Susumu, Slesinger, Paul A., Tucker, Stephen, Vandenberg, Carol A.   +17 more
core   +3 more sources

The Concise Guide to PHARMACOLOGY 2015/16:Voltage-gated ion channels [PDF]

, 2015
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org),
,, Alexander, Stephen Ph, Benson, Helen E, Catterall, William A, Davies, Jamie A, Faccenda, Elena, Kelly, Eamonn, Marrion, Neil, Pawson, Adam J, Peters, John A, Sharman, Joanna L, Southan, Christopher   +11 more
core   +4 more sources

Preferential assembly of heteromeric small conductance calcium-activated potassium channels. [PDF]

, 2015
The activation of small conductance calcium-dependent (SK) channels regulates membrane excitability by causing membrane hyperpolarization. Three subtypes (SK1-3) have been cloned, with each subtype expressed within the nervous system.
Benton, Bowden, Correa, D'Hoedt, Dale, Delisle, Denning, Goodchild, Gu, Ishii, Jan, Jenke, Jones, Kaczorowski, Kim, Kobori, Köhler, Lamy, Lima, Martin, Mei, Monaghan, Ngo-Anh, Nolting, Pedarzani, Pessia, Roncarati, Sailer, Sailer, Schumacher, Schwake, Shah, Shima, Stephens, Stewart, Stewart, Stocker, Stocker, Stoppini, Strobaek, Tuteja, Weatherall, Weatherall, Xia, Zhou   +44 more
core   +2 more sources

Kir5.1‐Mediated Changes in Renin‐Angiotensin‐Aldosterone System Balance in Salt Sensitive Hypertension

The FASEB Journal, 2019
Kir5.1 (encoded by Kcnj16 gene) is a member of the inwardly rectifying K + channel (Kir) family which is expressed in the kidney where it plays an essential role in the maintenance of electrolyte balance and blood pressure control.
Anna D. Manis, Oleg Palygin, Vladislav Levchenko, Matthew R. Hodges, Alexander Staruschenko   +4 more
openaire   +1 more source

Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels [PDF]

, 2003
Heteromultimerization between different potassium channel subunits can generate channels with novel functional properties and thus contributes to the rich functional diversity of this gene family.
Casamassima, Maria, D'Adamo, Maria Cristina, Pessia, Mauro, Tucker, Stephen J.   +3 more
core   +1 more source

Systematic Studies of Kir and TRP Channel mRNAs in the Norepinephrenergic Neurons of the Locus Coeruleus [PDF]

, 2011
Neurons in the Locus coeruleus (LC) play an important role in the central CO2 chemosensitivity. However, the molecular mechanisms for neuronal CO2 chemosensitivity remain unclear.
Tadepalli, Sakuntala Jyothirmayee
core   +1 more source