Results 191 to 200 of about 2,344,694 (261)

Developing a Fecal DNA Method With Blocking Primers to Determine Red Knots' (<i>Calidris canutus</i>) Diets Noninvasively. [PDF]

Ecol Evol
Teye CK, Grey EK, Kneidel A, Brown S, DiNunzio L.   +4 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

The prognosis of patients with gastrointestinal stromal tumors harboring the KIT exon 11 mutation: a retrospective cohort study. [PDF]

J Gastrointest Oncol
Shou C, Yang W, Wang X, Zhang Q, Yu J, Liang T.   +5 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Author Correction: Interfacial design strategies for stable and high-performance perovskite/silicon tandem solar cells on industrial silicon cells. [PDF]

Nat Commun
Fang L, Ren M, Li B, Liu X, Liang S, Petermann J, Gholipoor M, Zhao T, Sutter J, Fassl P, Weber H, Niemann R, Dai L, Guo R, Lemmer U, Fertig F, Paetzold UW.   +16 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Nilotinib revisited in GIST: salvage use in patients with severe imatinib toxicity. [PDF]

Oncologist
Falkenhorst J, Hohenberger P, Mancino G, Scrima A, Menge F, Fletcher BS, Reiff C, Lange V, Hamacher R, Bertram S, Rau FM, Zaun Y, Kaths M, Treckmann J, Jakob J, Mühlenberg T, Grunewald S, Krzeciesa D, Rauh D, Bauer S.   +19 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Targeting KIT prevents brain arteriovenous malformations driven by ALK1-deficient angiogenic endothelial cells. [PDF]

J Clin Invest
Drapé E, Carrier L, Cagnone G, Fuad ARM, Bizou M, Sanchez D, Anquetil T, Wang J, Touzani Walali HD, Gopinadhan A, van Vliet PP, Howard JP, Ibnat M, Andelfinger G, Winkler E, Larrivée B, Dubrac A.   +16 more
europepmc   +1 more source