Results 231 to 240 of about 2,344,694 (261)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Liver Endothelia Orchestrate MASH-Associated Macrophage Zonation Through FSTL1-ITGA4 Axis. [PDF]

Adv Sci (Weinh)
Sun L, Yue Z, Fang Z, Xu H, Du W, Ling Y, Liu J, Song P, He F, Duan J, Wang L.   +10 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Non-Coding RNAs in Gastrointestinal Stromal Tumors: Regulatory Networks, Drug Resistance, and Clinical Implications. [PDF]

Int J Mol Sci
Mandrakis G, Papadakos SP, Levidou G, Keratsa P, Christodoulou MI, Theocharis S.   +5 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Development and Evaluation of an Indirect ELISA for Strangles Based on an Untagged EQ8-SclF Fusion Protein. [PDF]

Vet Sci
Sun R, Zu H, Wang M, Guo W, Wang X, Yang Q.   +5 more
europepmc   +1 more source

Structure-based scaffold hopping reveals strategies to overcome oncogenic KIT and PDGFRA mutation-driven drug-resistance in GIST. [PDF]

Nat Commun
Schulz T, Beerbaum M, Scrima A, Jantzen H, Teuber A, Mühlenberg T, Ebel L, Garcia-Fossa F, George A, Berner N, Weisner J, Müller MP, Wilhelm S, Sievers S, Bauer S, Rauh D.   +15 more
europepmc   +1 more source

Cell Disruption and RNA Extraction from <i>Rhodococcus</i> and <i>Gordonia</i> Bacteria Grown in the Presence of Hydrophobic Organic Compounds and Heavy Metal Salts. [PDF]

Int J Mol Sci
Krivoruchko AV, Komarova LP, Maltseva PY, Tyan SM, Golysheva AA, Plotnitskaya NA, Kuyukina MS, Ivshina IB.   +7 more
europepmc   +1 more source

Impact of acute stress on gastric interstitial cells of Cajal disorder. [PDF]

Front Cell Dev Biol
Huang ZP, Wang K, Qiu H, Wan JW, Yang Z, Kong LW, Li ZY.   +6 more
europepmc   +1 more source

Low-Dose Cytarabine Plus G-CSF Induction in Pediatric M2 Acute Myeloid Leukemia: A Multicenter Study. [PDF]

Cancer Med
Ou W, Zhu X, Lu J, Wang H, Liao N, Liu Y, Jiang H, An Q, Yuan X, He H, Wang N, Luo J, Ju X, Wang QF, Yang M, Cheng C, Xiao P, Yang L, Gao L, Ribeiro RC, Hu S, Zhai X.   +21 more
europepmc   +1 more source