Results 31 to 40 of about 147 (124)

Chemoradiation of locally advanced biliary cancer: A PRISMA‐compliant systematic review

Cancer Medicine, Volume 13, Issue 23, December 2024.
This is a systematic review of the current evidence on “modern” chemoradiation for primary or recurrent unresectable biliary tract cancers. We have critically compared chemoradiation outcomes with those of other treatment options, seeking to determine whether specific chemoradiation modalities provide distinct advantages in terms of treatment efficacy ...
Silvia Bisello, Claudio Malizia, Filippo Mammini, Erika Galietta, Federica Medici, Gian Carlo Mattiucci, Francesco Cellini, Andrea Palloni, Luca Tagliaferri, Gabriella Macchia, Francesco Deodato, Savino Cilla, Giovanni Brandi, Alessandra Arcelli, Alessio G. Morganti   +14 more
wiley   +1 more source

Prevalence and Significance of AGR2 Expression in Human Cancer

Cancer Medicine, Volume 13, Issue 21, November 2024.
ABSTRACT Backround Anterior gradient 2 (AGR2) is a resident endoplasmic reticulum (ER) protein with a vital role in embryonal development, mucus maturation, tissue regeneration, and wound healing. Methods To determine the prevalence and clinical significance of AGR2 expression in cancer, a tissue microarray containing 14,966 tumors from 134 different ...
Nina Schraps, Jacob Constantin Port, Anne Menz, Florian Viehweger, Seyma Büyücek, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube‐Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Baris Mercanoglu, Nathaniel Melling, Thilo Hackert, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech, Florian Lutz   +31 more
wiley   +1 more source

Septin 9 expression regulates ‘don't eat me’ signals and identifies an immune–epithelial class of intrahepatic cholangiocarcinoma

Molecular Oncology, Volume 18, Issue 10, Page 2369-2392, October 2024.
Septin 9 is identified as a regulator of EMT and the host immune response. Intrahepatic cholangiocarcinoma (iCCA) was categorized into two groups: (1) ‘immune–epithelial’, with high expression of septin 9 and ‘don't eat me’ signal genes regulated by IFNγ/STAT1; and (2) ‘mesenchymal–ECM’, with high expression of vimentin, MMP7 and TIMP1.
Ting ting Cai, Christophe Desterke, Juan Peng, Jean Agnetti, Peixuan Song, Dalila Ouazib, Alexandre Dos Santos, Catherine Guettier, Didier Samuel, Ama Gassama‐Diagne   +9 more
wiley   +1 more source

CT Texture Analysis of Perihilar Cholangiocarcinoma—Associations With Tumor Grading, Tumor Markers and Clinical Outcome

Cancer Reports, Volume 7, Issue 9, September 2024.
ABSTRACT Background Texture analysis derived from computed tomography (CT) may provide clinically relevant imaging biomarkers associated with tumor histopathology. Perihilar cholangiocarcinoma is a malignant disease with an overall poor prognosis. Aims The present study sought to elucidate possible associations between texture features derived from CT ...
Jakob Leonhardi, Arsen Sabanov, Anne Kathrin Höhn, Robert Sucher, Daniel Seehofer, Matthias Mehdorn, Benedikt Schnarkowski, Sebastian Ebel, Timm Denecke, Hans‐Jonas Meyer   +9 more
wiley   +1 more source

Staining pattern of specific and cross‐reacting Melan‐A antibodies: A comparative study on 15,840 samples from 133 human tumor types

APMIS, Volume 132, Issue 7, Page 479-491, July 2024.
The Melan‐A (melanocyte antigen) protein, also termed ‘melanoma antigen recognized by T cells 1’ (MART‐1) is a protein with unknown function whose expression is specific for the melanocyte lineage. Antibodies against Melan‐A are thus used for identifying melanocytic tumors, but some Melan‐A antibodies show an additional – diagnostically useful – cross ...
Shiva Boroojerdi, Sören Weidemann, Anne Menz, Maximilian Lennartz, Sebastian Dwertmann Rico, Ria Schlichter, Simon Kind, Viktor Reiswich, Florian Viehweger, Ahmed Abdulwahab Bawahab, Doris Höflmeyer, Christoph Fraune, Natalia Gorbokon, Andreas M. Luebke, Claudia Hube‐Magg, Franziska Büscheck, Till Krech, Andrea Hinsch, Frank Jacobsen, Eike Burandt, Guido Sauter, Ronald Simon, Martina Kluth, Stefan Steurer, Sarah Minner, Andreas H. Marx, Christian Bernreuther, Till S. Clauditz, David Dum, Patrick Lebok   +29 more
wiley   +1 more source

Reoperation for post hepatectomy complications

ANZ Journal of Surgery, Volume 94, Issue 4, Page 660-666, April 2024.
Hepatectomy is associated with complications that may require return to theatre. However, there is a paucity in the literature identifying risk factors resulting in reoperation post‐hepatectomy. This paper has demonstrated that performing an additional major non‐hepatic procedure concurrent with the hepatectomy is a risk factor for return to theatre ...
Sam Yu, Jianliang Liu, Jessica Reid, Jessie Clarke, Suzanne Edwards, Guy Maddern   +5 more
wiley   +1 more source

Klatskin's tumor as a possible indication for liver transplants

, 2019
Klatskinov tumor (ili hilarni kolangiokarcinom) je ekstrahepatalni kolangiokarcinom koji nastaje na spoju lijevog i desnog hepatalnog žučnog voda.
Ermacora, Lucija
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Benign biliary inflammatory pseudotumor mimicking a Klatskin tumor.

, 2007
Most biliary tumors at the liver hilum are malignant and, when possible, require radical surgical resection. However, few rare benign lesions exist, for which the differential diagnosis with malignancy is important in order to avoid aggressive surgical ...
Gigot, Jean-François, Hubert, Catherine, Van Beers, Bernard, Gohy, Sophie, Deprez, Pierre Henri, Annet, Laurence, Lhommel, Renaud, Sempoux, Christine   +7 more
core  

Klatskin tumors and �Klatskin-mimicking lesions�: our 22-year experience.

Revista Española de Enfermedades Digestivas, 2018
Background and study purpose: Hilar cholangiocarcinoma, also known as Altemeier-Klatskin tumor, is a rare malignancy that arises in the confluence of the hepatic ducts of the porta hepatis. The prognosis is rather poor. Several lesions mimic these tumors and lead to a misdiagnosis, resulting in radical hepatic resections.
Konstantinos, Tsalis, Styliani, Parpoudi, Dimitrios, Kyziridis, Orestis, Ioannidis, Natalia-Antigoni, Savvala, Nikolaos, Antoniou, Savvas, Symeonidis, Dimitrios, Konstantaras, Ioannis, Mantzoros, Manousos-Georgios, Pramateftakis, Efstathios, Kotidis, Stamatios, Angelopoulos   +11 more
openaire   +2 more sources

Juxtapapillary duodenal diverticular bezor as an exceptional cause of biliary stent obstruction. Case report.

, 2007
INTRODUCTION: we describe the first case in literature of biliary stent obstruction by bezoar impaction in a iuxtapapillary duodenal diverticulum. CASE REPORT: this case illustrates an juxtapapillary duodenal diverticulum and bezoar in it causing ...
PISELLO, Franco, ARNONE, E, CUPIDO, Francesco, SCIUME', Carmelo, MODICA, Giuseppe, FACELLA, Tiziana, GERACI, Girolamo   +6 more
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