Results 241 to 250 of about 105,053 (315)

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao   +13 more
wiley   +1 more source

Optimization of 16S RNA Sequencing and Evaluation of Metagenomic Analysis with Kraken 2 and KrakenUniq. [PDF]

open access: yesDiagnostics (Basel)
Papa Mze N   +5 more
europepmc   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda   +12 more
wiley   +1 more source

The Evolution of Functional Amyloids and Their Impact on Host–Microbe Interactions

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
This review describes functional amyloids and highlights the importance of structural repetition and molecular mimicry that distinguish the amyloid fold. The authors describe how amyloid can be the last universal common ancestor of protein folds. The authors also discuss how microbes utilize functional amyloids and how the structural characteristics of
Divya Kolli   +3 more
wiley   +1 more source

Gender‐Based Differences in Gut Microbiota Composition in Response to Anxiety and Stress in Shooting and Archery Athletes

open access: yesBrain and Behavior, Volume 15, Issue 10, October 2025.
The study found that anxious athletes exhibited higher relative abundance of Firmicutes and lower levels of Actinobacteria. Predictive analyses revealed that male athletes showed increased endoplasmic reticulum protein processing, while anxious females demonstrated reduced base excision repair functions.
Yuhuan Wei   +7 more
wiley   +1 more source

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