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Global Prevalence of Colistin Resistance in Klebsiella pneumoniae from Bloodstream Infection: A Systematic Review and Meta-Analysis

Pathogens, 2022
Background: Among gram-negative bacteria, Klebsiella pneumoniae is one of the most common causes of healthcare-related infection. Bloodstream infections (BSIs) caused by Klebsiella pneumoniae are notorious for being difficult to treat due to resistance ...
Leonard Ighodalo Uzairue, Ali A. Rabaan, Fumilayo Ajoke Adewumi, Obiageli Jovita Okolie, Jamiu Bello Folorunso, Muhammed A. Bakhrebah, Mohammed Garout, Wadha A. Alfouzan, Muhammad A. Halwani, Aref A. Alamri, Shaima A. Halawani, Fatimah S. Alshahrani, Abdulkarim Hasan, Abbas Al Mutair, Saad Alhumaid, Johnson Etafo, Idorenyin Utip, Ikenna Maximillian Odoh, Nkolika S. Uwaezuoke   +18 more
doaj   +2 more sources

Hypervirulent Klebsiella pneumoniae [PDF]

Clinical Microbiology Reviews, 2019
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are often healthy.
Thomas A, Russo, Candace M, Marr
openaire   +4 more sources

Clinical distribution and drug resistance analysis of 3 342 strains of Klebsiella pneumoniae from 2018 to 2022

Zhongguo linchuang yanjiu, 2023
Objective To analyze the clinical distribution of Klebsiella pneumoniae isolates, screen for the multidrug resistance of Klebsiella pneumoniae strains to commonly used antimicrobial drugs, and provide reference for the prevention and control of ...
CHEN Mingxia*, MA Yue, YANG Congshan, MENG Shanshan
doaj   +1 more source

Hypervirulent Klebsiella pneumoniae

Infection and Drug Resistance, 2023
Hypervirulent Klebsiella pneumoniae (hvKP), especially multidrug-resistant hvKP (MDR-hvKP) infections, are distributed globally, and lead to several outbreaks with high pathogenicity and mortality in immunocompetent individuals. This is usually characterized by a rapidly metastatic spread resulting in multiple pyogenic tissue abscesses.
Junjun Chen, Huan Zhang, Xuelian Liao
openaire   +4 more sources

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

Nature Communications, 2021
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-associated infections, neonatal sepsis and community-acquired liver abscess, and is associated with chronic intestinal diseases.
M. Lam, R. Wick, Stephen C. Watts, L. Cerdeira, K. Wyres, K. Holt   +5 more
semanticscholar   +1 more source

Molecular characteristics and antimicrobial resistance profiles of Carbapenem-Resistant Klebsiella pneumoniae isolates at a tertiary hospital in Nanning, China

BMC Microbiology, 2023
Purpose Carbapenem resistant Klebsiella pneumoniae is associated with nosocomial infections and can cause high mortality, which poses great threat to human health.
Xianzhen Wei, Qiuxiang Li, Yu He, Linlin Li, Shan Li, Taijie Li   +5 more
doaj   +1 more source

Carbapenem-Resistant Klebsiella pneumoniae: Virulence Factors, Molecular Epidemiology and Latest Updates in Treatment Options

Antibiotics, 2023
Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety of community and hospital infections. Infections caused by carbapenem-resistant K.
T. Karampatakis, K. Tsergouli, P. Behzadi   +2 more
semanticscholar   +1 more source

Adult zebrafish infected by clinically isolated Klebsiella pneumoniae with different virulence showed increased intestinal inflammation and disturbed intestinal microbial biodiversity

BMC Infectious Diseases, 2023
Background Klebsiella pneumoniae is a pathogen that often infects patients in clinical practice. Due to its high virulent and drug resistance, infected patients are difficult to treat.
Xu Wang, Ting Li, Lu Zhou, Fan Tu, Xiaohong Rui, Ze Xu, Jun Liu, Futao Cao   +7 more
doaj   +1 more source

"Superbugs" with hypervirulence and carbapenem resistance in Klebsiella pneumoniae: the rise of such emerging nosocomial pathogens in China.

Science Bulletin, 2023
Although hypervirulent Klebsiella pneumoniae (hvKP) can produce community-acquired infections that are fatal in young and adult hosts, such as pyogenic liver abscess, endophthalmitis, and meningitis, it has historically been susceptible to antibiotics ...
Danni Pu, Jiankang Zhao, Kang Chang, Xianxia Zhuo, Bin Cao   +4 more
semanticscholar   +1 more source

Hypervirulent Klebsiella pneumoniae [PDF]

Open Forum Infectious Diseases, 2014
Abstract Hypervirulent strains of Klebsiella pneumoniae are associated with abscess formation, commonly hepatic, and metastatic spread, even in healthy patients. We describe a case of this clinical syndrome, genotypic and phenotypic features of the isolate, and briefly review epidemiology, clinical manifestations, and pathogenesis of ...
Patel, Payal K., Karchmer, Adolf, Russo, Thomas A.   +2 more
openaire   +3 more sources