Results 321 to 330 of about 387,179 (386)

Characteristics and In‐Hospital Outcomes of Patients With Septic Shock in the Adult Medical Intensive Care Unit of a Tertiary Hospital in Ethiopia: A Prospective Observational Study

open access: yesHealth Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aims Sepsis and septic shock are major healthcare problems, affecting millions of people around the world each year and claiming the lives of one‐sixth to one‐third of those affected. However, there is insufficient data on the characteristics and outcomes of septic shock patients in resource‐limited settings. This study aimed to
Amanuel Zeleke   +14 more
wiley   +1 more source

Gramicidin and chlorhexidine encapsulated in bicontinuous microemulsions: Antimicrobial activity performance and their impact on self‐assembly

open access: yesJournal of Surfactants and Detergents, Volume 28, Issue 4, Page 845-859, July 2025.
Interaction of gramicidin D (gD) and chlorhexidine (CH) with the surfactant monolayers of bicontinuous microemulsions. Abstract The utility of bicontinuous microemulsions (BMEs) as carriers of the antimicrobial peptide (AMP) gramicidin D and antiseptic chlorhexidine was investigated for possible topical delivery to chronic wounds.
Douglas G. Hayes   +6 more
wiley   +1 more source

Epithelial Atg5 Deficiency Intensifies Caspase‐11 Activation, Fueling Extracellular mtDNA Release to Activate cGAS–STING–NLRP3 Axis in Macrophages During Pseudomonas Infection

open access: yesMedComm, Volume 6, Issue 7, July 2025.
This work illuminates the essential role of epithelial ATG5 in defending against P. aeruginosa. Atg5 deficiency impairs bacterial clearance and aggravates inflammation via AKT/PI3K/NF‐κB, inflammasome activation, and pyroptosis. Mechanistically, impaired mitophagy intensifies mitochondrial damage.
Junyi Wang   +10 more
wiley   +1 more source

Characteristics of ESBL-positive Klebsiella pneumoniae isolated from paired children with and without diarrhea. [PDF]

open access: yesGut Pathog
Zhang Y   +9 more
europepmc   +1 more source

Phage and Endolysin Therapy Against Antibiotics Resistant Bacteria: From Bench to Bedside

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Synergistic effects of combining bacteriophages and antibiotics in antimicrobial therapy. The diagram illustrates key advantages of phage‐antibiotic synergy, including increased treatment effectiveness, reduced minimum inhibitory concentration (MIC) for drug‐resistant strains, enhanced biofilm eradication, and inhibition of resistant bacteria ...
Majid Taati Moghadam   +5 more
wiley   +1 more source

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