Results 311 to 320 of about 61,743 (326)

Altered expression of the KLF4 in colorectal cancers

Pathology - Research and Practice, 2006
KLF4 is an important regulator of cell proliferation and is maximally expressed in epithelial cells of the gastrointestinal tract. Inactivation of the KLF4 gene by genetic and epigenetic alterations has been reported in colorectal cancers, but the expression pattern of the KLF4 protein has not been studied.
Byung Joon, Choi, Yong Gu, Cho, Jae Whie, Song, Chang Jae, Kim, Su Young, Kim, Suk Woo, Nam, Nam Jin, Yoo, Jung Young, Lee, Won Sang, Park   +8 more
openaire   +2 more sources

Zebrafish KLF4 Is Essential for Primitive Haematopoiesis.

Blood, 2005
Abstract Gene knockout studies of Krüppel-like factors (KLFs) in mice have demonstrated key roles in organogenesis. EKLF (Klf1) plays an essential role in definitive erythropoiesis and b-globin gene expression, but primitive (yolk sac) erythropoiesis and embryonic globin gene expression are essentially normal.
Andrew C. Perkins, Melissa R. Gardiner
openaire   +1 more source

Bone Marrow Mesenchymal Stem Cell-Derived Exosomal KLF4 Alleviated Ischemic Stroke Through Inhibiting N6-Methyladenosine Modification Level of Drp1 by Targeting lncRNA-ZFAS1

Molecular Neurobiology, 2023
Qingsong Wang, Rongjun Xiao, Jun Peng, Zhengtao Yu, Jun-Qi Fu, Ying Xia   +5 more
semanticscholar   +1 more source

KLF4 signalling in carcinogenesis and epigenetic regulation of hTERT

Medical Hypotheses, 2018
Gene expression is crucial and tightly regulated to steer the development, differentiation, proliferation and even apoptosis of a cell. Each cell and tissue type shows a unique repertoire of transcription factors. Tissue micro-environmental regulation of epigenetic signature of a gene has been documented in many cases.
Suresh Singh, Yadav, Rohini Ravindran, Nair, Pramod Kumar, Yadava   +2 more
openaire   +2 more sources

Prognostic significance of NANOG and KLF4 for breast cancer

Breast Cancer, 2012
Some of the induced pluripotent stem cell (iPS cell)-inducing factors have been reported to be expressed in breast cancer. The aim of the present study was to examine the relationship between the expression of iPS cell-inducing factors and the prognosis of breast cancer patients.In 100 breast cancer patients, the expression of c-MYC, KLF4, NANOG, OCT4,
Takuya, Nagata, Yutaka, Shimada, Shinichi, Sekine, Ryota, Hori, Koshi, Matsui, Tomoyuki, Okumura, Shigeaki, Sawada, Junya, Fukuoka, Kazuhiro, Tsukada   +8 more
openaire   +2 more sources

Roles of Klf4 in embryonic stem cells

2015
Human and mouse ES cells are defined by their ability to confer self-renewal and differentiate into various cell types, making them an invaluable tool for investigation of Stem cell maintenance, differentiation, and reprogramming. Human ES cells have infinite potential for therapeutic applications.
openaire   +1 more source

KLF4 in Ovarian Cancer

Forum on Immunopathological Diseases and Therapeutics, 2016
Junming Yue, Baojin Wang, Ziyun Du, Lawrence M. Pfeffer   +3 more
openaire   +1 more source

Transcription factors TCF4 and KLF4 respectively control the development of the DC2A and DC2B lineages

Nature Immunology
Yiwen Zhu, Peiliang Cai, Ziyi Li, Shuangyan Zhang, Wan Ting Kong, Haiting Wang, Fei Gao, Yingying Zeng, Jiawen Qian, Bing Su, Zhaoyuan Liu, F. Ginhoux   +11 more
semanticscholar   +1 more source

Depletion of microRNA-92a Enhances the Role of Sevoflurane Treatment in Reducing Myocardial Ischemia–Reperfusion Injury by Upregulating KLF4

Cardiovascular Drugs and Therapy, 2022
Qianfu Wu, Haihui Wang, Fei He, Jiali Zheng, Hongjing Zhang, C. Cheng, Panwei Hu, Rong Lu, Guoliang Yan   +8 more
semanticscholar   +1 more source

Krüppel-like factor 4 (KLF4) in neuroblastoma

2011
The 4th Cross Strait Symposium on Pediatric Oncology, Hong Kong, 5-6 November 2010.
Ohira, M, Tsoi, LS, Tam, PKH, Ngan, ESW, Nakagawara, A   +4 more
openaire   +1 more source