Results 121 to 130 of about 644,059 (295)

Enhancing Amphibious Flipper‐Based Locomotion Through Terrain‐Dependent Bayesian Optimization of Central Pattern Generator Control

open access: yesAdvanced Robotics Research, EarlyView.
A sea turtle‐inspired amphibious robot uses simulation‐guided optimization to adapt its flipper coordination to different environments. Sensitivity analysis and multiobjective Bayesian optimization identify terrain‐dependent controllers that are validated on hardware.
Nnamdi C. Chikere, Yasemin Ozkan‐Aydin
wiley   +1 more source

The effect of surgery for multipleligament knee injuries on patellar position and patellofemoral function: a retrospective study

open access: yesJournal of Orthopaedic Surgery and Research
Background Patients who undergo reconstruction for multiligament knee injuries (MLKIs) often exhibit knee instability and poor overall knee function during postoperative follow-up.
Yuanping Liao   +4 more
doaj   +1 more source

Addressing sagittal plane imbalance in primary total knee arthroplasty: functional alignment outperforms kinematic and mechanical alignment techniques

open access: yesBone & Joint Open
Aims: Sagittal plane imbalance (SPI), or asymmetry between extension and flexion gaps, is an important issue in total knee arthroplasty (TKA). The purpose of this study was to compare SPI between kinematic alignment (KA), mechanical alignment (MA), and ...
Victor A. van de Graaf   +4 more
doaj   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang   +6 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang   +16 more
wiley   +1 more source

Inconsistent relationship between body weight/body mass index prior to total knee arthroplasty and the 12-year survival

open access: yes, 2019
Background: The primary hypothesis was that body weight (BW) and body mass index (BMI) significantly impact the long-term survival rate after implantation of a mobile bearing total knee arthroplasty (TKA).Methods: A national, multicentric, retrospective ...
Jenny, J.Y.   +23 more
core   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

open access: yesAdvanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Comparison of transdermal and oral anti-inflammatory drugs on immediate post-operative pain control in total knee arthroplasty: a randomized controlled trial

open access: yesArthroplasty
Background Oral nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used as multimodal pain-control medications in total knee arthroplasty (TKA), while topical NSAIDs are commonly used for chronic pain conditions.
Nonn Jaruthien   +6 more
doaj   +1 more source

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