Results 61 to 70 of about 365,718 (293)

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Image-based robotic (ROSA® knee system) total knee arthroplasty with inverse kinematic alignment compared to conventional total knee arthroplasty

Journal of Orthopaedic Surgery and Research
Introduction In 2020, 368 million people globally were affected by knee osteoarthritis, and prevalence is projected to increase with 74% by 2050. Relatively high rates of dissatisfactory results after total knee arthroplasty (TKA), as reported by ...
Henriëtte M. Eijking, Isobel M. Dorling, Emil H. van Haaren, Roel Hendrickx, Thijs Nijenhuis, Martijn G.M. Schotanus, Lee Bouwman, Jasper Most, Bert Boonen   +8 more
doaj   +1 more source

Arthroplasty of a Charcot knee

Orthopedic Review, 2010
The Charcot knee - or neuropathic arthropathy - presents a considerable challenge to the orthopaedic surgeon. Caused by a combination of sensory, motor and autonomic neuropathy, it was originally described as an arthritic sequelae of neurosyphilis. In today's western orthopaedics it is more often caused by diabetes.
Babazadeh, S, Stoney, JD, Lim, K, Choong, PFM   +3 more
openaire   +4 more sources

Preoperative Total Iron‐Binding Capacity Is a Potential Surrogate Marker of Long‐Term Outcomes After Pancreatectomy for Pancreatic Cancer

Annals of Gastroenterological Surgery, EarlyView.
Preoperative low serum total iron‐binding capacity (TIBC) was associated with poorer overall survival and recurrence‐free survival after pancreatectomy for pancreatic cancer. These findings suggest that preoperative serum TIBC may serve as a simple surrogate marker for long‐term outcomes in patients undergoing pancreatectomy.
Taishi Yamane, Hiromitsu Hayashi, Hiroshi Sawayama, Takashi Matsumoto, Toru Takematsu, Takanobu Yamao, Yuki Kitano, Tatsunori Miyata, Hirohisa Okabe, Masaaki Iwatsuki   +9 more
wiley   +1 more source

Unicompartmental Knee Arthroplasty: Modes of Failure and Conversion to Total Knee Arthroplasty [PDF]

Joints, 2017
AbstractDespite the excellent success rates of the modern unicompartmental knee arthroplasty (UKA), results of knee replacement registries still shows a relatively high revision and failure rate for UKA, especially when compared with traditional total knee arthroplasty (TKA). Bearing dislocation continues to be advocated as the predominant mechanism of
Vasso, Michele, Corona, Katia, D’apolito, Rocco, Mazzitelli, Giuseppe, Schiavone Panni, Alfredo   +4 more
openaire   +3 more sources

Orthobiologic Injections Adjunctive to Cartilage‐Preserving Surgery May Improve Outcomes for Focal Knee Chondral Defects: A Systematic Review of Randomized Controlled Trials With Subgroup Meta‐analyses

Arthroscopy, EarlyView.
Purpose To perform a systematic review evaluating the efficacy of orthobiologic injections as adjuncts to cartilage‐preserving surgery in improving clinical, radiographic, and histologic outcomes in adults with focal knee cartilage defects. Methods Four databases (PubMed, MEDLINE, EMBASE, and Scopus) were searched through September 2025 for randomized ...
Benjamin Blackman, Alexandru Pulbere, Seth Ybema, Marc Daniel Bouchard, Prushoth Vivekanantha, Praveen Sritharan, Darren de SA, Olufemi R. Ayeni, Jeffrey Kay   +8 more
wiley   +1 more source

Reliability of radiographic knee and hip osteoarthritis classification between radiologists and orthopaedic surgeons

Journal of Orthopaedic Surgery and Research
Introduction Osteoarthritis (OA) is a common and disabling joint condition that requires accurate assessment for effective management. Variability in radiographic classification of OA severity can impact diagnostic accuracy and treatment decisions.
Henriette M. Eijking, Robin Voskuilen, Pieter Tilman, Martijn G. M. Schotanus, Bob Jong, Bert Boonen, Jasper Most   +6 more
doaj   +1 more source

Knee arthroplasty rating

The Journal of Arthroplasty, 1992
A number of rating systems used to evaluate the results of total knee arthroplasty exist. Many of these systems are based on different concepts, and might be expected to give divergent results. To see if this was so, the authors examined a consecutive series of 235 posterior stabilized knee arthroplasties recording the results according to five rating ...
R, Binazzi, M, Soudry, L A, Mestriner, J N, Insall   +3 more
openaire   +2 more sources

Knee and Ankle Arthroplasty in Hemophilia [PDF]

Journal of Clinical Medicine, 2017
Today, major surgical procedures can be safely performed in hemophilic patients with chronic arthropathy, using available factor concentrates. In this setting, total knee replacement is considered the “gold standard”, while the use of total ankle replacement is still debated.
Solimeno L, Pasta G
openaire   +2 more sources

The Forgotten Joint Score Shows High Correlation With Established Anterior Cruciate Ligament Reconstruction Patient‐Reported Outcome Measures While Capturing Joint Awareness and Functional Recovery: A Systematic Review

Arthroscopy, EarlyView.
Purpose To systematically review and analyze the existing literature on the use of the Forgotten Joint Score‐12 (FJS‐12) in patients undergoing anterior cruciate ligament reconstruction (ACLR), with the aim of evaluating its effectiveness as a complementary tool to traditional patient‐reported outcome measures (PROMs) in assessing postoperative ...
Helena Son, Vincent Yu, Prushoth Vivekanantha, Marc Daniel Bouchard, Kanto Nagai, Sachin Tapasvi, Darren de SA   +6 more
wiley   +1 more source