Results 141 to 150 of about 371,395 (290)

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor   +7 more
wiley   +1 more source

Magneto‐responsive fibers and fabrics for soft systems

open access: yesFlexMat, EarlyView.
Abstract The combination of functional materials in fiber form has led to a surge in the integration of functional fibers and fabrics into soft systems that span sensing, communication, and actuation domains. A key subset is magnetic fibers and fabrics.
Hanlin Zhu   +8 more
wiley   +1 more source

Navigating Workplace Bullying: A Critical Theory Exploration of Lecturers' Experiences in a Higher Education Context

open access: yesHuman Resource Development Quarterly, EarlyView.
ABSTRACT Workplace bullying (WB) remains a pervasive concern across all sectors, including higher education institutions (HEIs), where shifting power dynamics, performance pressures, and transformation mandates often create fertile ground for systemic abuse.
Helen Meyer
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

open access: yesJournal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini   +3 more
wiley   +1 more source

IGF2BP3 Overexpression Accelerates Osteoarthritis Progression by Promoting Glycolysis via m6A‐Dependent Stabilization of ECM1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT N6‐methyladenosine (m6A) plays a critical role in osteoarthritis (OA) pathogenesis. This study investigates the role of the m6A reader insulin‐like growth factor 2 mRNA‐binding protein 3 (IGF2BP3) in OA progression. OA models were established in vivo through destabilization of the medial meniscus (DMM) surgery in mice and in vitro by ...
Xing‐Shi Yuan   +8 more
wiley   +1 more source

Association between walking gait biomechanical changes after anterior cruciate ligament injury or reconstruction and the development of osteoarthritis: A systematic review

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Anterior cruciate ligament (ACL) injury and reconstruction significantly increase the risk of knee osteoarthritis (OA). Biomechanical alterations during walking are frequently suggested contributors to OA development. This systematic review aims to determine the association between walking gait biomechanical changes following ACL ...
Jérôme Riera   +4 more
wiley   +1 more source

Spatiotemporal dynamics of brain function network during proprioception rehabilitation after anterior cruciate ligament reconstruction: A randomized trial

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
The improvement of proprioceptive function after ACLR is related to the optimization of spatiotemporal dynamics of SM, CC, DM, CB and VI functional networks. Rehabilitation optimization can incorporate visual–cognitive dual‐task exercises. Abstract Purpose In this study, we aimed to examine the dynamic functional network connectivity (dFNC) patterns ...
Xiaoyun Zhuang   +7 more
wiley   +1 more source

Diagnostic value of the patellar tendon–lateral trochlear ridge distance and the patellar tendon–trochlear groove angle in differentiating lateral patellar instability from malalignment‐induced patellofemoral pain

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare the patellar tendon–lateral trochlear ridge (PT‐LTR) distance and patellar tendon–trochlear groove angle (PT‐TGA) between patients with lateral patellar instability (LPI) and those with malalignment‐induced patellofemoral pain (PFP), and to evaluate their differential diagnostic validity.
Razvan Pacala   +5 more
wiley   +1 more source

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