Results 201 to 210 of about 416,194 (299)

Clinical study on Knee Three Needles combined with ultra-short wave for knee osteoarthritis. [PDF]

open access: yesMedicine (Baltimore)
Yu X   +6 more
europepmc   +1 more source

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

open access: yesInterdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang   +3 more
wiley   +1 more source

Efficacy of Oral Vitamin K2 Supplementation in Experimental Knee Osteoarthritis. [PDF]

open access: yesMetabolites
Uzun E   +7 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

open access: yesInterdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He   +3 more
wiley   +1 more source

3D printing of cell‐free implants: A promising avenue for cartilage regeneration and joint preservation

open access: yesInterdisciplinary Medicine, EarlyView.
This article explores the potential of 3D‐printed, cell‐free implants or devices for cartilage regeneration. It highlights the benefits of using biomaterial‐driven activation and modulation of ESCPs for endogenous healing of heterogeneous tissues, addressing challenges in implant design, repair mechanisms, and regulatory hurdles to create scalable ...
Liangbin Zhou   +11 more
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

open access: yesJournal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini   +3 more
wiley   +1 more source

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