Results 151 to 160 of about 480,132 (361)

Diclofenac solution (Pennsaid) in the management of osteoarthritis of the knee : Patient implications [PDF]

open access: yes, 2009
Topical diclofenac sodium (pennsaid) is a non-steroidal-anti- inflammatory drug that is used to manage the recurrent pain and symptoms of osteoarthritis of the knee. Pennsaid is applied topically, absorbed cutaneously and concentrates locally at the site
Banning, M
core  

Electrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.
Karlien Mul   +15 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

A Pain in the … Knee [PDF]

open access: yesThe American Journal of Sports Medicine, 2016
openaire   +2 more sources

Tranexamic Acid Use in Hip Arthroscopy Reduces Bleeding Without Increased Risk of Major Complications: A Systematic Review

open access: yesArthroscopy, EarlyView.
Purpose To critically evaluate the impact of tranexamic acid (TXA) on hip arthroscopy outcomes, including its effects on bleeding, functional recovery, postoperative pain, complications, intraoperative visualization, and surgical efficiency. Methods A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic ...
Paul B. Walker   +6 more
wiley   +1 more source

Correlation Between Catastrophizing and Pain in Knee Osteoarthritis Patients Awaiting Total Knee Replacement

open access: yesOrthopaedic Journal of Sports Medicine
Objectives: Osteoarthritis is a leading cause of pain and disability, particularly in the elderly population. Total knee replacement is the primary treatment for advanced knee osteoarthritis, but not all individuals who undergo total knee arthroplasty ...
GC Campos   +5 more
doaj   +1 more source

Smaller Lateral‐to‐Medial Tibial Plateau Ratios Are Strongly Correlative With Anterior Cruciate Ligament Tears and Reconstruction Failures

open access: yesArthroscopy, EarlyView.
Purpose To compare the anterior–posterior distance ratio of the lateral‐to‐medial tibial plateau (LTP/MTP) among 3 patient groups: those with intact anterior cruciate ligaments (ACLi), primary ACL tears (ACLp), and failed ACL reconstructions (ACLf).
Hansel E. Ihn   +6 more
wiley   +1 more source

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