Results 141 to 150 of about 872,819 (289)

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

open access: yesAdvanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing   +9 more
wiley   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

Large Oncosomes Induce Pro‐Metastatic Stromal‐Myeloid Reprogramming

open access: yesAdvanced Science, EarlyView.
Large oncosomes systemically reprogram bone marrow mesenchymal stem cells through innate nucleic acid sensing, driving inflammatory and immunosuppressive remodeling that supports a metastasis‐permissive bone marrow environment, revealing a novel tumor‐host communication axis in cancer. ABSTRACT Bone metastasis can be facilitated by systemic remodeling,
Taylon Felipe Silva   +18 more
wiley   +1 more source

Knee Surgery: Total Knee Replacement or Partial Knee Replacement [PDF]

open access: yesOrthopedics and Rheumatology Open Access Journal, 2016
openaire   +1 more source

Innovations in Knee Replacement

open access: yes, 2010
Includes descriptive metadata provided by producer in MP3 file: "Vanderbilt Sports Medicine - Vanderbilt Health Radio Interviews - Innovations in Knee Replacement." By Debbie Alan and Cory L. Calendine, MD.Cory Calendine, M.D.
Calendine, Cory, Alan, Debbie
core  

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

open access: yesAdvanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu   +16 more
wiley   +1 more source

Knee replacement [PDF]

open access: yesJournal of Clinical Orthopaedics and Trauma, 2011
  +4 more sources

Redefining knee replacement

open access: yesOrthopaedics & Traumatology: Surgery & Research, 2017
P-A, Vendittoli, W, Blakeney
openaire   +2 more sources

Enriched Soil Organic Carbon Underpins Long‐Term Stable Crop Productivity Across China's Croplands

open access: yesAdvanced Science, EarlyView.
Quantifying the nonlinear relationships and causal effects of soil organic carbon (SOC) on crop stability reveals specific critical thresholds and saturation points. This partitions the national SOC spectrum into three functional phases. Integrating these spatial delineations with high‐resolution maps of marginal gains pinpoints regions with the ...
Yuyang Huang   +11 more
wiley   +1 more source

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