Results 181 to 190 of about 83,783 (313)
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
Simultaneous bilateral total knee replacement in a patient with achondroplasia and severe varus deformity: a case report. [PDF]
Chernov D +6 more
europepmc +1 more source
Background Pain is the hallmark symptom of osteoarthritis (OA) and its biological drivers remain poorly understood. While the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular regulatory T cells (Tregs), is not well understood. Methods We performed omics profiling of peripheral blood from 46
Marie Binvignat +26 more
wiley +1 more source
Fear of Falling After Total Knee Replacement: A Saudi Experience. [PDF]
Aljuhani T +7 more
europepmc +1 more source
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin +15 more
wiley +1 more source
Self-reported physical activity and risk of primary knee replacement for osteoarthritis: a competing risks cohort analysis. [PDF]
Peng H +8 more
europepmc +1 more source

