Advanced Science, EarlyView.The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan +10 more
wiley +1 more source
Weight-bearing 3D morphology of valgus knees: A comparative study within a varus dominant cohort. [PDF]
J Exp OrthopChi F +3 more
europepmc +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Advanced Science, EarlyView.Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
A modified quadriceps snip technique in primary total knee arthroplasty for hemophilic stiff knees: a retrospective case series. [PDF]
Front Med (Lausanne)Wang K +8 more
europepmc +1 more source
A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring
Advanced Science, EarlyView.This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali +7 more
wiley +1 more source
Comparison of clinical outcomes between cruciate-retaining and posterior-stabilized total knee arthroplasty in patients with mild to moderate patellofemoral joint osteoarthritis. [PDF]
Front SurgJia Y +6 more
europepmc +1 more source
Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals
Advanced Science, EarlyView.A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu +13 more
wiley +1 more source
Data‐Driven Design of Self‐Adhesive Epidermal Electrodes and Sensors
Advanced Science, EarlyView.This work presents self‐adhesive, stretchable epidermal electrodes and sensors developed through a data‐driven design framework that integrates artificial neural networks with genetic algorithms. By tailoring optimization objectives, either maximizing electrical conductivity and adhesion or enhancing piezoresistive sensitivity, the study enables the ...
Xuan Li +10 more
wiley +1 more source
Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation
Advanced Science, EarlyView.Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang +7 more
wiley +1 more source
Early-onset rice body synovitis of the knee in children under three years: a case series and review of the literature. [PDF]
Arch Orthop Trauma SurgZhu L +7 more
europepmc +1 more source