Results 31 to 40 of about 146,940 (312)

Cartilage lesions are not the main factor influencing pain and functional impairment in early knee osteoarthritis: a multivariate analysis on intra- and extra-articular factors affecting symptoms in over 200 knees

Bone & Joint Open
Aims: To investigate the correlation between symptoms, in terms of pain and functional scores, and the extent of cartilage damage as well as other intra- and extra-articular factors in patients suffering from early knee osteoarthritis (OA).
Luca Bianco Prevot, Alessandro Bensa, Pietro S Randelli, Giuseppe Filardo   +3 more
doaj   +1 more source

Are varus knees contracted? Reconciling the literature

, 2017
Purpose: There is direct literature conflict regarding coronal plane contracture or laxity in the end-stage varus\ud osteoarthritic knee. Understanding the preoperative soft tissue status is important for optimizing the soft tissue envelope during total ...
Garg, Gautam, Vakili, Ali, Roe, John A., John Roe, McAuliffe, Michael J., Crawford, Ross W., Michael J McAuliffe, Whitehouse, Sarah L., Sarah L Whitehouse, Ali Vakili, Gautam Garg, Ross Crawford   +11 more
core   +1 more source

Transcutaneous carbon dioxide improves joint inflammation and articular cartilage degeneration in rat osteoarthritis models

Bone & Joint Research
Aims: As global ageing and life expectancy increase, the prevalence and incidence of osteoarthritis (OA) are expected to rise. Transcutaneous carbon dioxide (CO2) therapy has been shown to promote muscle regeneration, fracture healing, strengthen ...
Changxin Li, Hideki Moriyama, Shota Inoue, Junpei Hatakeyama, Daisuke Takamura, Hanlin Jiang, Yoshitada Sakai, Toshihiro Akisue   +7 more
doaj   +1 more source

High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis

Bone & Joint Research
Aims: To examine cellular and molecular mechanisms of meniscal degeneration, including matrix degradation and inflammation, and identify therapeutic targets for osteoarthritis interventions. Methods: Meniscal tissue samples were collected from a total of
Juncheng Yao, Haolin Ke, Guangxin Huang, Xuan Wang, Zhe Li, Yan Shao, Huabin Chen, Jianying Pan, Daozhang Cai, Chun Zeng   +9 more
doaj   +1 more source

Caring for patients with periprosthetic femoral fractures across England and Wales in 2021: results of the National Hip Fracture Database Facilities Audit

Bone & Joint Open, 2023
Aims: The aim of this study was to describe services available to patients with periprosthetic femoral fracture (PPFF) in England and Wales, with focus on variation between centres and areas for care improvement.
Conor S. Jones, William G. P. Eardley, Antony Johansen, Dominic S. Inman, Jonathan T. Evans   +4 more
doaj   +1 more source

Computational analysis of tibial slope adjustment with fixed-bearing medial unicompartmental knee arthroplasty in ACL- and PCL-deficient models

Bone & Joint Research, 2022
Aims: A functional anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) has been assumed to be required for patients undergoing unicompartmental knee arthroplasty (UKA). However, this assumption has not been thoroughly tested. Therefore,
Hyuck M. Kwon, Jin-Ah Lee, Yong-Gon Koh, Kwan K. Park, Kyoung-Tak Kang   +4 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Prevalence of abnormal findings in 230 knees of asymptomatic adults using 3.0 T MRI [PDF]

, 2020
OBJECTIVE: To identify abnormalities in asymptomatic sedentary individuals using 3.0 Tesla high-resolution MRI. MATERIALS AND METHODS: The cohort comprised of 230 knees of 115 uninjured sedentary adults (51 males, 64 females; median age: 44 years).
Moon, JC, Di Laura, A, Fotiadou, A, Torlasco, C, Hart, AJ, D'Silva, A, Horga, LM, Sharma, S, Hirschmann, AC, Henckel, J   +9 more
core   +2 more sources

High rate of tibial debonding and failure in a popular knee replacement: a follow-up review

Bone & Joint Open, 2022
Aims: Total knee arthroplasty (TKA) is a common and safe orthopaedic procedure. Zimmer Biomet's NexGen is the second most popular brand of implant used in the UK. The primary cause of revision after the first year is aseptic loosening.
David Keohane, Gerard A. Sheridan, Eric Masterson   +2 more
doaj   +1 more source

Total knee arthroplasty in valgus knee

Orthopaedics & Traumatology: Surgery & Research, 2010
Total knee arthroplasty (TKA) in valgus knee has the reputation of being more difficult than in well aligned or varus knee, and there is no management consensus. Results on a continuous series of 100 TKAs on valgus knee were compared to the literature data, to define surgical strategy adapted to the various types of valgus knee.
Williot, A., Rosset, P., Favard, L., Brilhault, J., Burdin, P.   +4 more
openaire   +2 more sources