Results 201 to 210 of about 277,472 (265)

Investigating the contribution of rare non-coding variants in BRCA1, BRCA2 and PALB2 to hereditary breast cancer. [PDF]

NPJ Breast Cancer
Zhao Q, Li N, Marinovic E, McInerny S, Zethoven M, Devereux L, Canson DM, Spurdle AB, Scott RJ, James PA, Campbell IG.   +10 more
europepmc   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

A redox sensor in protein kinase A regulatory subunit Iα regulates vasodilation and protects against hypertension. [PDF]

Redox Biol
Rudyk O, Braga A, Wheatcroft N, Bonzanni M, Prysyazhna O, Korneh MNA, Green HLH, Zhou Y, Zhang M, Gourine AV, Eaton P.   +10 more
europepmc   +1 more source

Inhibition of high risk HPV31 E8^E2 repressor activity enables differentiation-independent genome amplification and E4 expression. [PDF]

PLoS Pathog
Rehm TM, Straub E, Doorbar J, Grundhoff A, Günther T, Blümke P, Iftner T, Stubenrauch F.   +7 more
europepmc   +1 more source

CRISPR and Beyond: Genome-Editing Strategies in Retinal Stem Cell Research. [PDF]

Cells
Woronkowicz M, Thomas MN, Saram SJ, Carr AF, Alonso-Carriazo Fernandez A, Butt Z, Skopiński P, Ramsden CM.   +7 more
europepmc   +1 more source

WormTagDB: a systematic survey of endogenously tagged proteins in Caenorhabditis elegans and roadmap toward the tagged proteome. [PDF]

G3 (Bethesda)
Leyhr J, Chi Q, Zeng L, Li X, Cao B, Shen EZ, Zou W, Sherwood DR.   +7 more
europepmc   +1 more source

A nanobody-based degron system for targeted protein knockdown in Dictyostelium discoideum. [PDF]

BMC Mol Cell Biol
Hashimura H, Fujishiro S, Shimada N, Adachi T, Sugita T, Kuwana S, Sawai S.   +6 more
europepmc   +1 more source

Highly efficient gene editing via targeted Cas9 insertion into chicken housekeeping gene. [PDF]

Poult Sci
Jung KM, Klein R, Mony SI, Chen PR, Lee K, Lee HJ.   +5 more
europepmc   +1 more source