Results 131 to 140 of about 254,216 (351)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Archives of Metallurgy and Materials, 2014 Ductile cast iron (GS) has noticed great development in last decades and its boom has no analogue in history humankind. Ductile iron has broaden the use of castings from cast iron into areas, which where exclusively domains for steel castings.
Vasková I. +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
The Effects of Equivalence Ratio on Pressure Wave Development during Knocking Combustion
, 2018 A knocking combustion in a one-dimensional constant volume reactor has been simulated with a detailed chemical kinetic mechanism of n-heptane premixed gases by using the compressible Navier-Stokes equations.
N. Oshima +3 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier +12 more
wiley +1 more source
Analisa kinerja metode hybrid port knocking pada sistem operasi linux [PDF]
, 2015 Hybrid port knocking(HPK) merupakan pengembangan metode port knockingyang menggunakan tiga konsep yaitu port knocking, steganografi, dan mutual authentication untuk meningkatan keamanan jaringan.
Jusuf, Monica Sabrina
core
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Knocking as an Input Method for Home Security Systems
, 2016 Home security is one of the most critical concerns in daily life. Traditional home security typically depends heavily on locks; however, it is inconvenient for people to carry numerous keys simply to open doors.
CHOU CHIEN-HSING; CHEN HUAN-LUN
core
Towards port-knocking authentication methods for mobile cloud computing
, 2017 Mobile cloud computing (MCC) is an increasingly popular research topic, partly due to the widespread adoption of mobile devices and cloud services among individual and organizational users. Security and privacy of data-at-rest and data-in-transit are two
Muhammad Shiraz +9 more
core +1 more source
Advanced Engineering Materials, EarlyView.This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele +2 more
wiley +1 more source