Results 91 to 100 of about 13,654,993 (361)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Research Involvement and EngagementBackground Young women living with perinatal infections of the Human Immunodeficiency Virus (YWLPHIV) in low- and middle-income countries are more likely to be challenged by social and health inequities, which can make adherence to life-long treatment ...
Lynn Hendricks +5 more
doaj +1 more source
A Personalized English Learning Material Recommendation System Based on Knowledge Graph
, 2021 Yiqin Huang, Jiang Zhu
openalex +2 more sources
Towards an ontology-based platform-independent framework for developing KBE systems in the aerospace industry [PDF]
, 2013 Aerospace engineering is considered to be one of the most complex and advanced branches of engineering. The use of knowledge based engineering (KBE) technologies has played a major role in automating routine design activities in view of supporting the ...
Sanya, Isaac, Shehab, Essam
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Cross-domain Knowledge Distillation for Retrieval-based Question Answering Systems
, 2021 Cen Chen +5 more
openalex +1 more source
Ada as an implementation language for knowledge based systems [PDF]
Debates about the selection of programming languages often produce cultural collisions that are not easily resolved. This is especially true in the case of Ada and knowledge based programming.
Rochowiak, Daniel
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Proposed Multi-ST Model for Collaborating Multiple Robots in Dynamic Environments
MachinesCoverage path planning describes the process of finding an effective path robots can take to traverse a defined dynamic operating environment where there are static (fixed) and dynamic (mobile) obstacles that must be located and avoided in coverage path ...
Hai Van Pham +4 more
doaj +1 more source
Knowledge-based scheduling for flexible manufacturing systems [PDF]
, 1988 Yongsheng Yang +2 more
openalex +1 more source