The AI Bus architecture for distributed knowledge-based systems [PDF]
The AI Bus architecture is layered, distributed object oriented framework developed to support the requirements of advanced technology programs for an order of magnitude improvement in software costs.
Schultz, Roger D., Stobie, Iain
core +1 more source
Proposed Multi-ST Model for Collaborating Multiple Robots in Dynamic Environments
Coverage path planning describes the process of finding an effective path robots can take to traverse a defined dynamic operating environment where there are static (fixed) and dynamic (mobile) obstacles that must be located and avoided in coverage path ...
Hai Van Pham +4 more
doaj +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Temporal and contextual knowledge in model-based expert systems [PDF]
A basic paradigm that allows representation of physical systems with a focus on context and time is presented. Paragon provides the capability to quickly capture an expert's knowledge in a cognitively resonant manner.
Heher, Dennis, Toth-Fejel, Tihamer
core +1 more source
A Smart Fuzzy Risk Assessment System for Epidemic Prevention on Cruise Ships
Cruise ships are a popular vacation choice, but their usually crowded conditions and enclosed spaces make them vulnerable to outbreaks of airborne infectious diseases. Risk assessment (RA) of epidemic outbreaks on cruise ships has traditionally relied on
Georgios Triantafyllou +4 more
doaj +1 more source
Knowledge Management Systems in the Polish Private, State and Foreign Owned Companies
The importance of knowledge management for enterprises increased significantly in the recent years. In this paper one element of knowledge management will be considered, namely knowledge management systems (KMS).
Marcin Soniewicki, Łukasz Wawrowski
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Validation of highly reliable, real-time knowledge-based systems [PDF]
Knowledge-based systems have the potential to greatly increase the capabilities of future aircraft and spacecraft and to significantly reduce support manpower needed for the space station and other space missions.
Johnson, Sally C.
core +1 more source
GENESIS, a knowledge-based genetic engineering simulation system for represntation of genetic data and experiment planning [PDF]
Peter Friedland +4 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source

