Results 131 to 140 of about 13,654,993 (361)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Collaborative Environments. Considerations Concerning Some Collaborative Systems [PDF]

It is obvious, that all collaborative environments (workgroups, communities of practice, collaborative enterprises) are based on knowledge and between collaboration and knowledge management there is a strong interdependence.
Mihaela I. MUNTEAN
core  

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Detecting and predicting the topic change of Knowledge-based Systems: A topic-based bibliometric analysis from 1991 to 2016

Knowledge-Based Systems, 2017
Yi Zhang, Hongshu Chen, Jie Lu, Guangquan Zhang   +3 more
semanticscholar   +1 more source

Intelligent Operational Risk Management Using the Enhanced FMEA Method and Artificial Intelligence—A Case Study

Applied Sciences
The main purpose of the article is to demonstrate how large language models (LLMs) can enhance and automate the Failure Modes and Effects Analysis (FMEA) method to improve the identification, assessment, and management of operational risk in modern ...
Kinga Ratajszczak, Alexandru-Vasile Oancea, Agnieszka Misztal, Nadia Ionescu, Laurențiu Mihai Ionescu, Anna Wencek   +5 more
doaj   +1 more source

OWL2 benchmarking for the evaluation of knowledge based systems. [PDF]

PLoS One, 2017
Khan SA, Qadir MA, Abbas MA, Afzal MT, Afzal MT.   +4 more
europepmc   +1 more source

Knowledge systems in health in sub-Saharan Africa: results of a questionnaire-based survey [PDF]

, 2014
Chris Zielinski, Derege Kebede, Peter Ebongue Mbondji, Issa Sanou, Wenceslas Kouvividila, Paul-Samson Lusamba-Dikassa   +5 more
openalex   +1 more source

Real-time application of knowledge-based systems [PDF]

The Rapid Prototyping Facility (RPF) was developed to meet a need for a facility which allows flight systems concepts to be prototyped in a manner which allows for real-time flight test experience with a prototype system. This need was focused during the
Brumbaugh, Randal W., Duke, Eugene L.
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source