Results 141 to 150 of about 6,074,163 (287)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Construction of dynamic stochastic simulation models using knowledge-based techniques [PDF]
Over the past three decades, computer-based simulation models have proven themselves to be cost-effective alternatives to the more structured deterministic methods of systems analysis.
Shiva, Sajjan G., Williams, M. Douglas
core +1 more source
DEVELOPMENT OF CHILDREN COMMUNICATION AT PRIMARY SCHOOL AGE IN COMPUTER-ORIENTED ENVIRONMENT
Інформаційні технології і засоби навчання, 2010 The research results of information technologies influence as education environment constituents on development of children communication at primary school age are presented in the article.
Galina P. Lavrentieva
doaj
Knowledge based system for control rod programming of BWRs.
, 1988 Takaharu Fukuzaki +4 more
openalex +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Using fuzzy logic to integrate neural networks and knowledge-based systems [PDF]
Outlined here is a novel hybrid architecture that uses fuzzy logic to integrate neural networks and knowledge-based systems. The author's approach offers important synergistic benefits to neural nets, approximate reasoning, and symbolic processing. Fuzzy
Yen, John
core +1 more source
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
, 2009 This paper describes an alternative approach to knowledge based systems in engineering than traditional geometry or explicit knowledge focused systems.
Halliday, S. +3 more
core
A study of costume design consultation system based on knowledge engineering.
, 1988 Mitsuo Nagamachi +3 more
openalex +2 more sources