Results 51 to 60 of about 9,026,652 (293)

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

FEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka, Takahiro Ogawa, Rikako Tsukida, Keiichi Noguchi, David Hibbett, Yoko Katayama, Makoto Yoshida   +6 more
wiley   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

FEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri, Haruka Tachibana, Daisuke Kawasaki, Taichi Chisuga, Toma Kashima, Shinya Fushinobu, Fumitaka Kudo, Tadashi Eguchi, Akimasa Miyanaga   +8 more
wiley   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

An Intelligent Knowledge-Based and Customizable Home Care System Framework with Ubiquitous Patient Monitoring and Alerting Techniques

Sensors, 2012
This study develops and integrates an efficient knowledge-based system and a component-based framework to design an intelligent and flexible home health care system.
Yen-Lin Chen, Hsin-Han Chiang, Chao-Wei Yu, Chuan-Yen Chiang, Chuan-Ming Liu, Jenq-Haur Wang   +5 more
doaj   +1 more source

A Method for Knowledge Representation to Design Intelligent Problems Solver in Mathematics Based on Rela-Ops Model

IEEE Access, 2020
Knowledge-base is a fundamental platform in the architecture of an intelligent system. Relations and operators are popular knowledge in practice knowledge domains.
Hien D. Nguyen, Nhon V. Do, Vuong T. Pham, Ali Selamat, Enrique Herrera-Viedma   +4 more
doaj   +1 more source

ŠVALERI: EKSPERTNI SISTEMI SU ULOVILI SVOJ PLIJEN A POSLIJE SU BRZO „HVATALI MAGLU“ [PDF]

Zbornik Radova Ekonomskog Fakulteta u Istočnom Sarajevu, 2014
Expert Systems (ES) have been developed by small laboratories or passionate individuals and they were financed from R&D funds. At some times it was even done in "free time". Thus, the ES shell completed with a report on the completed work.
Zoltan Baracskai, Jolán Velencei
doaj   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Business Intelligence Systems Accounting Integration in Romania. a Comparative Analysis

Studies and Scientific Researches: Economics Edition, 2010
Business Intelligence (BI) systems have penetrated the Romanian market, providing a real decision support by integrating and synthesizing a large variety of information available in real time, anywhere in the world, including through mobile terminals ...
Daniela Postolache (Males)
doaj   +1 more source

Equivariant Filter Design for Kinematic Systems on Lie Groups [PDF]

arXiv, 2020
It is known that invariance and equivariance properties for systems on Lie groups can be exploited in the design of high performance and robust observers and filters for real-world robotic systems. This paper proposes an analysis framework that allows any kinematic system on a Lie group to be embedded in a natural manner into an equivariant kinematic ...
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source