Results 71 to 80 of about 14,636,841 (366)
Knowledge-base is a fundamental platform in the architecture of an intelligent system. Relations and operators are popular knowledge in practice knowledge domains.
Hien D. Nguyen +4 more
doaj +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
The interaction between humans and knowledge management systems : rethinking the future [PDF]
In this workshop position paper, we propose a study to understand the importance of knowledge management systems among academics in Saudi higher education institutions, admitting that knowledge workers and Knowledge Management Systems are valuable ...
Almujally, Nouf, Joy, Mike
core
Today, patients generate a massive amount of health records through electronic health records (EHRs). Extracting usable knowledge of patients’ pathological conditions or diagnoses is essential for the reasoning process in rule-based systems to ...
Chao Ou-Yang +4 more
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Assessing Ontology Mappings on a Level of Concepts and Instances
In recent years, the number of domain ontologies on the Internet has been steadily increasing. Many ontologies describe overlapping universes of discourse in various ways, therefore, the need for an efficient ontology alignment method is required ...
Marcin Pietranik +2 more
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source

