Results 81 to 90 of about 10,246,525 (323)
A Smart Fuzzy Risk Assessment System for Epidemic Prevention on Cruise Ships
IEEE AccessCruise ships are a popular vacation choice, but their usually crowded conditions and enclosed spaces make them vulnerable to outbreaks of airborne infectious diseases. Risk assessment (RA) of epidemic outbreaks on cruise ships has traditionally relied on
Georgios Triantafyllou +4 more
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
An integrated two-stage methodology for optimising the accuracy of performance classification models
Technological and Economic Development of Economy, 2017 In this paper we propose a two-stage methodology to classify the non-banking financial institutions (NFIs) based on their financial performance. The first stage of the methodology consists of grouping the companies in similar financial performance ...
Adrian Costea +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Supporting early design stages of technical systems by knowledge-based simulation [PDF]
, 1999 Uwe Langer, Axel Lehmann
openalex +1 more source
Knowledge-Based Planning for Human-Robot Collaborative Tasks
IEEE AccessHuman-robot collaboration is a promising alternative to full automation and manual labour. Collaborative robots are considered safe and individual robot actions can often be easily programmed, for example, by physical hand-guiding.
Alexandre Angleraud +2 more
doaj +1 more source
A Diabetes Management Information System with Glucose Prediction
Information, 2018 Diabetes has become a serious health concern. The use and popularization of blood glucose measurement devices have led to a tremendous increase on health for diabetics. Tracking and maintaining traceability between glucose measurements, insulin doses and
Cláudio Augusto Silveira Lélis +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source