Results 121 to 130 of about 11,762,702 (302)

Diocese of Quebec [cartographic material] /

Map of the Diocese of Quebec, Canada, showing towns and administrative borders.; Inset: New Brunswick.; Prime meridian: Greenwich.; Plate [6] from: The Colonial Church Atlas, Third edition, London: Society for Promoting Christian Knowledge, [1850]; Also ...
Society for Promoting Christian Knowledge (Great Britain)
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Diocese of Adelaide [Western Australia] [cartographic material] /

Map showing the area of the Diocese of Adelaide in Western Australia and featuring locations of churches and towns.; Prime meridian: Greenwich; Plate [26] from: The Colonial Church Atlas, Third edition, London: Society for Promoting Christian Knowledge,
Society for Promoting Christian Knowledge (Great Britain)
core  

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Integrating spatial analytics and explainable machine learning to analyse multi-pollutant mortality burdens in Africa

Discover Public Health
Air pollution in Africa is a critical public health problem that has claimed many lives, especially in places where urbanisation and vehicle emissions are increasing. The present study used spatial analysis and a hybrid Genetic Algorithm–Machine Learning
Gideon Mazuruse, Retius Chifurira, Temesgen Zewotir, Knowledge Chinhamu   +3 more
doaj   +1 more source

Diocese of Cape Town [cartographic material] : [Western District] / drawn & engraved by J. Archer.

Map of the western part of the Diocese of Cape Town showing towns and administrative borders.; Prime meridian: Greenwich; Plate [13] from: The Colonial Church Atlas, Third edition, London: Society for Promoting Christian Knowledge, [1850]; Also available
Society for Promoting Christian Knowledge (Great Britain)
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Diocese of Antigua [cartographic material] /

Map of the Diocese of Antigua, West Indies, showing towns, the Archdeaconeries of Antigua and St. Christopher, and locations of churches.; Prime meridian: Greenwich.; Plate [11] from: The Colonial Church Atlas, Third edition, London: Society for ...
Society for Promoting Christian Knowledge (Great Britain)
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Differences in demographics and clinical outcomes in older, middle-aged, and younger adults with low back pain receiving chiropractic care

Chiropractic & Manual Therapies
Background The evidence on age-related differences in outcomes in patients seeking chiropractic care for low back pain is limited. The aims of this study were to (i) to explore differences in patient characteristics and symptoms between older, middle ...
L. A. Hansen, J. Hartvigsen, R. K. Jensen   +2 more
doaj   +1 more source