Results 161 to 170 of about 35,424,542 (378)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Knowledge acquisition for knowledge-based systems: Notes on the state-of-the-art [PDF]
, 1989 John H. Boose, Brian R. Gaines
openalex +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Knowledge base design for decision support in respirator therapy [PDF]
, 1989 Nosrat Shahsavar +5 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Knowledge base methodology: Methodology for first Engineering Script Language (ESL) knowledge base [PDF]
The primary goal of reusing software components is that software can be developed faster, cheaper and with higher quality. Though, reuse is not automatic and can not just happen. It has to be carefully engineered.
Izygon, Michel E., Peeris, Kumar
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Crafting Knowledge Based Systems Expert Systems Made Realistic by Waiters and Nielson (Wiley Interscience, 1988) [PDF]
, 1989 Robin Singer
openalex +1 more source
On Knowledge Excavation Based on University Library Knowledge Base
Asian Social Science, 2009 Knowledge excavation is a new information processing technology. Nowadays, knowledge excavation has been widely applied to the university library management. Knowledge excavation in university library knowledge bases has already been playing an important role in improving the management of university libraries and inevitably will play a more profound ...
openaire +2 more sources