Results 201 to 210 of about 30,775,009 (307)

Learning translation skills with a knowledge-based tutor [PDF]

, 1983
Stefano A. Cerri, Marie-France Merger
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Memorizing is Not Enough: Deep Knowledge Injection Through Reasoning [PDF]

arXiv
Although large language models (LLMs) excel in knowledge recall and reasoning, their static nature leads to outdated information as the real world evolves or when adapting to domain-specific knowledge, highlighting the need for effective knowledge injection.
arxiv  

A knowledge-based approach to online document retrieval system design [PDF]

, 1986
Gautam Biswas, James C. Bezdek, Robert L. Oakman   +2 more
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

КОНЦЕПЦІЯ ВИКОРИСТАННЯ ГЕОІНФОРМАТИКИ В ПОБУДОВІ ІНФОРМАЦІЙНО-КЕРУЮЧОЇ СИСТЕМИ «ВИЩА ШКОЛА УКРАЇНИ»

Інформаційні технології і засоби навчання, 2010
У статті викладені основні концептуальні положення використання методів геоінформатики для побудови інформаційно-керуючої системи «вища школа України».
Kostiantyn O. Meteshkin, Ihor M. Patrakeiev, Oksana V. Postoienko   +2 more
doaj  

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Neuron, 2019
F. Koopmans, P. Nierop, Maria Andres-Alonso, Andrea Byrnes, T. Cijsouw, Marcelo P Coba, L. N. Cornelisse, Ryan J. Farrell, Hana L. Goldschmidt, D. Howrigan, Natasha K. Hussain, Cordelia Imig, A. D. Jong, Hwajin Jung, M. Kohansalnodehi, B. Kramarz, N. Lipstein, R. Lovering, H. MacGillavry, Vittoria Mariano, H. Mi, M. Ninov, David Osumi-Sutherland, R. Pielot, K. Smalla, Haiming Tang, K. Tashman, R. Toonen, C. Verpelli, Rita Reig-Viader, Kyoko Watanabe, J. Weering, T. Achsel, Ghazaleh Ashrafi, N. Asi, Tyler C. Brown, P. Camilli, M. Feuermann, Rebecca E. Foulger, P. Gaudet, Anoushka Joglekar, Alexandros K. Kanellopoulos, R. Malenka, R. Nicoll, C. Pulido, J. D. Juan-Sanz, M. Sheng, €. ThomasC.S, Hagen U. Tilgner, C. Bagni, Alex Baye´s, T. Biederer, N. Brose, John Jia, En Chua, D. Dieterich, Eckart D. Gundelfinger, C. Hoogenraad, Richard L. Huganir, R. Jahn, P. Kaeser, Eunjoon Kim, M. Kreutz, Peter S. McPherson, B M Neale, V. O’Connor, D. Posthuma, Timothy A. Ryan, C. Sala, G. Feng, Steven E. Hyman, P. Thomas, A. Smit, M. Verhage   +73 more
semanticscholar   +1 more source

Crafting Knowledge Based Systems Expert Systems Made Realistic by Waiters and Nielson (Wiley Interscience, 1988) [PDF]

, 1989
Robin Singer
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Knowledge Generation for Zero-shot Knowledge-based VQA [PDF]

arXiv
Previous solutions to knowledge-based visual question answering~(K-VQA) retrieve knowledge from external knowledge bases and use supervised learning to train the K-VQA model. Recently pre-trained LLMs have been used as both a knowledge source and a zero-shot QA model for K-VQA and demonstrated promising results.
arxiv