Results 51 to 60 of about 841,080 (310)

Offline Knowledge Base and Attention-Driven Semantic Communication for Image-Based Applications in ITS Scenarios

Big Data and Cognitive Computing
Communications in intelligent transportation systems (ITS) face explosive data growth from applications such as autonomous driving, remote diagnostics, and real-time monitoring, imposing severe challenges on limited spectrum, bandwidth, and latency ...
Yan Xiao, Xiumei Fan, Zhixin Xie, Yuanbo Lu   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

SOME APPROACHES TO THE REPRESENTATION OF REALITY FOR SOLVING PROBLEMS OF SPECIALISTS’ EDUCATION IN MODERN EDUCATIONAL ENVIRONMENT

Открытое образование (Москва), 2016
Article represents the features of modern educational environment for training specialists in the fi eld of aerospace robotics. Training requirements of modern specialists are pointed.
Svetlana V. Zenkina, Vasilij M. Trembach
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Knowledge management system as a basis for smart learning

Открытое образование (Москва), 2018
The purpose of the study is to develop an approach to improve information support for the development of the contents of higher education programs and teaching methodological materials.
Natalia V. Dneprovskaya
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Research on ontology-based construction risk knowledge base development in deep foundation pit excavation

Journal of Asian Architecture and Building Engineering
Facing the massive amount of risk management data for deep foundation pit excavation (DFPE) construction, how to store and utilize these data to prevent the occurrence of risk events is an urgent problem that needs to be solved. The goal of this research
Yuan Chen, Bingge Liang, Hang Hu
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Application of artificial intelligence technologies for analysis of polymer composite materials in production conditions

π-Economy
This article addresses the development and research of a modern information system aimed at effective recognition and comprehensive analysis of composite material particles.
Farakhov Rustam, Burnashev Rustam, Matrenina Olga   +2 more
doaj   +1 more source