Results 81 to 90 of about 4,480,263 (341)
Performance analysis of a message-oriented knowledge-base [PDF]
, 1987 First-order Horn logic is a useful formalism to design knowledge-based systems. When implemented on a sequential von Neumann computer, the main limitation of such systems is performance.
Bic, Lubomir +2 more
core
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Development of science and technology in a knowledge-based organization from the intellectual capital’s perspective [PDF]
مطالعات مدیریت راهبردی, 2020 The foundation of an organization and its transformation into a knowledge organization depend deeply on its various aspects, so that if it is not provided with its basic infrastructure and infrastructure, any attempt at it will fail.
mohammad reza zahedi +2 more
doaj
The ReSIST Resilience Knowledge Base
, 2007 We describe a prototype knowledge base that uses semantic web technologies to provide a service for querying a large and expanding collection of public data about resilience, dependability and security.
Anderson, Tom +5 more
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Knowledge Acquisition for Diagnosis of Skin Diseases as an Initial Platform for an Expert System
Journal of Health Management & Informatics, 2018 Background: The diagnosis of skin diseases, especially in patients suffering from more than one disease or having similar symptoms, is very complex and access to the knowledge of skin diseases makes the design of an expert system easier.
Fatemeh Rangraz Jeddi +2 more
doaj
A knowledge base architecture for distributed knowledge agents [PDF]
A tuple space based object oriented model for knowledge base representation and interpretation is presented. An architecture for managing distributed knowledge agents is then implemented within the model.
Riedesel, Joel, Walls, Bryan
core +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
DECISION MAKING PROCESS IN CARDIAC SURGERY – CONCEPT OF BUILDING AN EXPERT SYSTEM [PDF]
Management Systems in Production Engineering, 2013 The fundamental goal of modern information technology is to support decision making process in organizations, for both routine and highly complex problems, based on heterogeneous data sources.
Tomasz HRAPKOWICZ +4 more
doaj