Results 81 to 90 of about 4,570,213 (290)
Development of science and technology in a knowledge-based organization from the intellectual capital’s perspective [PDF]
مطالعات مدیریت راهبردی, 2020 The foundation of an organization and its transformation into a knowledge organization depend deeply on its various aspects, so that if it is not provided with its basic infrastructure and infrastructure, any attempt at it will fail.
mohammad reza zahedi +2 more
doaj
A knowledge base architecture for distributed knowledge agents [PDF]
A tuple space based object oriented model for knowledge base representation and interpretation is presented. An architecture for managing distributed knowledge agents is then implemented within the model.
Riedesel, Joel, Walls, Bryan
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Knowledge Acquisition for Diagnosis of Skin Diseases as an Initial Platform for an Expert System
Journal of Health Management & Informatics, 2018 Background: The diagnosis of skin diseases, especially in patients suffering from more than one disease or having similar symptoms, is very complex and access to the knowledge of skin diseases makes the design of an expert system easier.
Fatemeh Rangraz Jeddi +2 more
doaj
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Innovation: Exploring the knowledge base [PDF]
New types of knowledge, and new ways of organising the production of it, may emerge as knowledge producers respond to the challenges posed by a changing society.
Jan Fagerberg, Koson Sapprasert
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Planetary Defense Mitigation Gateway: A One-Stop Gateway for Pertinent PD-Related Contents
Data, 2019 Planetary Defense (PD) has become a critical effort of protecting our home planet by discovering potentially hazardous objects (PHOs), simulating the potential impact, and mitigating the threats.
Ishan Shams +13 more
doaj +1 more source
Learning over Knowledge-Base Embeddings for Recommendation
, 2018 State-of-the-art recommendation algorithms -- especially the collaborative filtering (CF) based approaches with shallow or deep models -- usually work with various unstructured information sources for recommendation, such as textual reviews, visual ...
Ai, Qingyao +3 more
core +2 more sources